Thyroid function in critically ill patients
E Fliers, AC Bianco, L Langouche… - The lancet Diabetes & …, 2015 - thelancet.com
Patients in the intensive care unit (ICU) typically present with decreased concentrations of
plasma tri-iodothyronine, low thyroxine, and normal range or slightly decreased …
plasma tri-iodothyronine, low thyroxine, and normal range or slightly decreased …
Non-thyroidal illness in the ICU: a syndrome with different faces
G Van den Berghe - Thyroid, 2014 - liebertpub.com
Background: Critically ill patients typically present with low or low-normal plasma thyroxine,
low plasma triiodothyronine (T3), increased plasma reverse T3 (rT3) concentrations, in the …
low plasma triiodothyronine (T3), increased plasma reverse T3 (rT3) concentrations, in the …
[HTML][HTML] Thyroid hormone concentrations in severely or critically ill patients with COVID-19
W Gao, W Guo, Y Guo, M Shi, G Dong, G Wang… - Journal of …, 2021 - Springer
Objective COVID-19 is a new coronavirus infectious disease. We aimed to study the
characteristics of thyroid hormone levels in patients with COVID-19 and to explore whether …
characteristics of thyroid hormone levels in patients with COVID-19 and to explore whether …
[HTML][HTML] Thyroid allostasis–adaptive responses of thyrotropic feedback control to conditions of strain, stress, and developmental programming
A Chatzitomaris, R Hoermann, JE Midgley… - Frontiers in …, 2017 - frontiersin.org
The hypothalamus–pituitary–thyroid feedback control is a dynamic, adaptive system. In
situations of illness and deprivation of energy representing type 1 allostasis, the stress …
situations of illness and deprivation of energy representing type 1 allostasis, the stress …
Beyond Low Plasma T3: Local Thyroid Hormone Metabolism during Inflammation and Infection
A Boelen, J Kwakkel, E Fliers - Endocrine reviews, 2011 - academic.oup.com
Decreased serum thyroid hormone concentrations in severely ill patients were first reported
in the 1970s, but the functional meaning of the observed changes in thyroid hormone levels …
in the 1970s, but the functional meaning of the observed changes in thyroid hormone levels …
[HTML][HTML] Mortality risk profiling of Staphylococcus aureus bacteremia by multi-omic serum analysis reveals early predictive and pathogenic signatures
Staphylococcus aureus bacteremia (SaB) causes significant disease in humans, carrying
mortality rates of∼ 25%. The ability to rapidly predict SaB patient responses and guide …
mortality rates of∼ 25%. The ability to rapidly predict SaB patient responses and guide …
[HTML][HTML] Thyroid dysfunction in COVID-19 patients
R Baldelli, E Nicastri, N Petrosillo, L Marchioni… - Journal of …, 2021 - Springer
Purpose “Non thyroidal illness syndrome”(NTIS) or “euthyroid sick syndrome”(ESS) is a
possible biochemical finding in euthyroid patients with severe diseases. It is characterized …
possible biochemical finding in euthyroid patients with severe diseases. It is characterized …
[HTML][HTML] Nonthyroidal illness syndrome: To treat or not to treat? Have we answered the question? A review of metanalyses
Background and Objective Nonthyroidal Illness Syndrome (NTIS) occurs in approximately
70% of patients admitted to Intensive Care Units (ICU) s and has been associated with …
70% of patients admitted to Intensive Care Units (ICU) s and has been associated with …
Nonthyroidal illness syndrome across the ages
L Langouche, A Jacobs… - Journal of the Endocrine …, 2019 - academic.oup.com
In conditions of acute illness, patients present with reduced plasma T3 concentrations
without a concomitant rise in TSH. In contrast, plasma concentrations of the inactive …
without a concomitant rise in TSH. In contrast, plasma concentrations of the inactive …
Thyroid hormones in critical illness
The thyroid gland produces hormones that primarily regulate cellular metabolism, have wide-
ranging pleiotropic effects, and are essential for life. During critical illness, the most active …
ranging pleiotropic effects, and are essential for life. During critical illness, the most active …