[HTML][HTML] Nanoparticle drug delivery systems for synergistic delivery of tumor therapy
D Chen, X Liu, X Lu, J Tian - Frontiers in Pharmacology, 2023 - frontiersin.org
Nanoparticle drug delivery systems have proved anti-tumor effects; however, they are not
widely used in tumor therapy due to insufficient ability to target specific sites, multidrug …
widely used in tumor therapy due to insufficient ability to target specific sites, multidrug …
Current advances in non‐viral gene delivery systems: Liposomes versus extracellular vesicles
In the past decade, nucleic acid‐based drugs have emerged as an extremely promising
approach for silencing specific disease‐related genes and targeting undruggable ones …
approach for silencing specific disease‐related genes and targeting undruggable ones …
[HTML][HTML] Analysis of PEG-lipid anchor length on lipid nanoparticle pharmacokinetics and activity in a mouse model of traumatic brain injury
LE Waggoner, KF Miyasaki, EJ Kwon - Biomaterials Science, 2023 - pubs.rsc.org
Traumatic brain injury (TBI) affects millions of people worldwide, yet there are currently no
therapeutics that address the long-term impairments that develop in a large portion of …
therapeutics that address the long-term impairments that develop in a large portion of …
Screening for lipid nanoparticles that modulate the immune activity of helper T cells towards enhanced antitumour activity
Lipid nanoparticles (LNPs) can be designed to potentiate cancer immunotherapy by
promoting their uptake by antigen-presenting cells, stimulating the maturation of these cells …
promoting their uptake by antigen-presenting cells, stimulating the maturation of these cells …
[HTML][HTML] mRNA-based therapeutics in cancer treatment
H Sun, Y Zhang, G Wang, W Yang, Y Xu - Pharmaceutics, 2023 - mdpi.com
Over the past two decades, significant technological innovations have led to messenger
RNA (mRNA) becoming a promising option for developing prophylactic and therapeutic …
RNA (mRNA) becoming a promising option for developing prophylactic and therapeutic …
Lipid nanoparticles optimized for targeting and release of nucleic acid
Y Jia, X Wang, L Li, F Li, J Zhang… - Advanced Materials, 2024 - Wiley Online Library
Lipid nanoparticles (LNPs) are currently the most promising clinical nucleic acids drug
delivery vehicles. LNPs prevent the degradation of cargo nucleic acids during blood …
delivery vehicles. LNPs prevent the degradation of cargo nucleic acids during blood …
Theranostic Lipid Nanoparticles for Renal Cell Carcinoma
X Mao, G Wang, Z Wang, C Duan, X Wu… - Advanced …, 2023 - Wiley Online Library
Renal cell carcinoma (RCC) is a common urological malignancy and represents a leading
threat to healthcare. Recent years have seen a series of progresses in the early diagnosis …
threat to healthcare. Recent years have seen a series of progresses in the early diagnosis …
[HTML][HTML] Small tech, big impact: Agri-nanotechnology journey to optimize crop protection and production for sustainable agriculture
The world's climate shifts rapidly, leading to increasingly severe and volatile weather,
negatively impacting crop yields. To produce long-lasting crops, cutting-edge …
negatively impacting crop yields. To produce long-lasting crops, cutting-edge …
Design and fabrication of intracellular therapeutic cargo delivery systems based on nanomaterials: current status and future perspectives
H Ma, F Xing, Y Zhou, P Yu, R Luo, J Xu… - Journal of Materials …, 2023 - pubs.rsc.org
Intracellular cargo delivery, the introduction of small molecules, proteins, and nucleic acids
into a specific targeted site in a biological system, is an important strategy for deciphering …
into a specific targeted site in a biological system, is an important strategy for deciphering …
Evolving tumor characteristics and smart nanodrugs for tumor immunotherapy
W Sun, S Xie, SF Liu, X Hu, D Xing - International Journal of …, 2024 - Taylor & Francis
Typical physiological characteristics of tumors, such as weak acidity, low oxygen content,
and upregulation of certain enzymes in the tumor microenvironment (TME), provide survival …
and upregulation of certain enzymes in the tumor microenvironment (TME), provide survival …