[HTML][HTML] Use of radiomic features and support vector machine to distinguish Parkinson's disease cases from normal controls

Y Wu, JH Jiang, L Chen, JY Lu, JJ Ge… - Annals of …, 2019 - ncbi.nlm.nih.gov
Background Parkinson's disease (PD) is an irreversible neurodegenerative disease. The
diagnosis of PD based on neuroimaging is usually with low-level or deep learning features …

Abnormal pattern of brain glucose metabolism in Parkinson's disease: replication in three European cohorts

SK Meles, RJ Renken, M Pagani, LK Teune… - European journal of …, 2020 - Springer
Abstract Rationale In Parkinson's disease (PD), spatial covariance analysis of 18 F-FDG
PET data has consistently revealed a characteristic PD-related brain pattern (PDRP). By …

Validation of parkinsonian disease‐related metabolic brain patterns

LK Teune, RJ Renken, D Mudali… - Movement …, 2013 - Wiley Online Library
Background The objective of this study was to validate disease‐related metabolic brain
patterns for Parkinson's disease, multiple system atrophy, and progressive supranuclear …

Automatic covariance pattern analysis outperforms visual reading of 18F‐fluorodeoxyglucose‐positron emission tomography (FDG‐PET) in variant progressive …

R Buchert, F Wegner, HJ Huppertz… - Movement …, 2023 - Wiley Online Library
Background To date, studies on positron emission tomography (PET) with 18F‐
fluorodeoxyglucose (FDG) in progressive supranuclear palsy (PSP) usually included PSP …

Rational therapeutic approaches to progressive supranuclear palsy

M Stamelou, R de Silva, O Arias-Carrión, E Boura… - Brain, 2010 - academic.oup.com
Progressive supranuclear palsy is a sporadic and progressive neurodegenerative disease,
most often presenting as a symmetric, akinetic-rigid syndrome with postural instability …

Differential diagnosis of parkinsonian syndromes using PCA-based functional imaging features

PG Spetsieris, Y Ma, V Dhawan, D Eidelberg - Neuroimage, 2009 - Elsevier
In the current paper, we describe methodologies for single subject differential diagnosis of
degenerative brain disorders using multivariate principal component analysis (PCA) of …

Voxel-wise analysis of [123I]β-CIT SPECT differentiates the Parkinson variant of multiple system atrophy from idiopathic Parkinson's disease

C Scherfler, K Seppi, E Donnemiller, G Goebel… - Brain, 2005 - academic.oup.com
To investigate the cerebral dopamine transporter status in the early stages of the parkinson-
variant of multiple system atrophy (MSA-P), 15 patients with MSA-P and a disease duration …

[HTML][HTML] Multiclass classification of FDG PET scans for the distinction between Parkinson's disease and atypical parkinsonian syndromes

G Garraux, C Phillips, J Schrouff, A Kreisler… - NeuroImage: Clinical, 2013 - Elsevier
Most available pattern recognition methods in neuroimaging address binary classification
problems. Here, we used relevance vector machine (RVM) in combination with booststrap …

Abnormal metabolic brain network associated with Parkinson's disease: replication on a new European sample

P Tomše, L Jensterle, M Grmek, K Zaletel, Z Pirtošek… - Neuroradiology, 2017 - Springer
Purpose The purpose of this study was to identify the specific metabolic brain pattern
characteristic for Parkinson's disease (PD): Parkinson's disease-related pattern (PDRP) …

Catechol‐O‐methyltransferase Val158Met and the risk of dyskinesias in Parkinson's disease

LML De Lau, D Verbaan, J Marinus… - Movement …, 2012 - Wiley Online Library
Background: The A‐allele of the catechol‐O‐methyltransferase (COMT) Val158Met
polymorphism is associated with decreased enzymatic activity and higher dopamine …