Epilepsy in children

R Guerrini - The Lancet, 2006 - thelancet.com
Summary 10· 5 million children worldwide are estimated to have active epilepsy. Over the
past 15 years, syndrome-oriented clinical and EEG diagnosis, and better aetiological …

Tailoring materials for epilepsy imaging: from biomarkers to imaging probes

J Zhao, C Wang, W Sun, C Li - Advanced Materials, 2022 - Wiley Online Library
Excising epileptic foci (EF) is the most efficient approach for treating drug‐resistant epilepsy
(DRE). However, owing to the vast heterogeneity of epilepsies, EF in one‐third of patients …

Objective interictal electrophysiology biomarkers optimize prediction of epilepsy surgery outcome

N Kuroda, M Sonoda, M Miyakoshi, H Nariai… - Brain …, 2021 - academic.oup.com
Researchers have looked for rapidly-and objectively-measurable electrophysiology
biomarkers that accurately localize the epileptogenic zone. Promising candidates include …

Role of subdural electrocorticography in prediction of long-term seizure outcome in epilepsy surgery

E Asano, C Juhasz, A Shah, S Sood, HT Chugani - Brain, 2009 - academic.oup.com
Since prediction of long-term seizure outcome using preoperative diagnostic modalities
remains suboptimal in epilepsy surgery, we evaluated whether interictal spike frequency …

Origin and propagation of epileptic spasms delineated on electrocorticography

E Asano, C Juhász, A Shah, O Muzik, DC Chugani… - …, 2005 - Wiley Online Library
Purpose: Ictal electrographic changes were analyzed on intracranial electrocorticography
(ECoG) in children with medically refractory epileptic spasms to assess the dynamic …

Phase‐amplitude coupling between interictal high‐frequency activity and slow waves in epilepsy surgery

H Motoi, M Miyakoshi, TJ Abel, JW Jeong, Y Nakai… - …, 2018 - Wiley Online Library
Objective We hypothesized that the modulation index (MI), a summary measure of the
strength of phase‐amplitude coupling between high‐frequency activity (> 150 Hz) and the …

Epilepsy surgery outcome in children with tuberous sclerosis complex evaluated with α-[11C] methyl-L-tryptophan positron emission tomography (PET)

K Kagawa, DC Chugani, E Asano… - Journal of Child …, 2005 - journals.sagepub.com
Tuberous sclerosis complex is commonly associated with medically intractable seizures. We
previously demonstrated that high uptake of α-[11C] methyl-L-tryptophan (AMT) on positron …

The diagnostic value of initial video-EEG monitoring in children—review of 1000 cases

E Asano, C Pawlak, A Shah, J Shah, AF Luat… - Epilepsy Research, 2005 - Elsevier
OBJECTIVE:: We retrospectively reviewed the clinical utility of initial video-EEG monitoring
in a series of 1000 children suspected of epileptic disorders. METHODS:: The ages of …

Reciprocal control of translation and transcription in autism spectrum disorder

F Longo, E Klann - EMBO reports, 2021 - embopress.org
Autism spectrum disorder (ASD) is a neurodevelopmental disorder characterized by deficits
in social communication and the presence of restricted patterns of interest and repetitive …

Corpus callosotomy in the modern era: origins, efficacy, technical variations, complications, and indications

C Markosian, S Patel, S Kosach, RR Goodman… - World Neurosurgery, 2022 - Elsevier
Corpus callosotomy is among the oldest surgeries performed for drug-resistant epilepsy.
Since it was first performed in 1940, numerous studies have assessed its outcomes in …