[HTML][HTML] Insights into Drug Cardiotoxicity from Biological and Chemical Data: The First Public Classifiers for FDA DICTrank
Drug-induced cardiotoxicity (DICT) is a major concern in drug development, accounting for
10–14% of postmarket withdrawals. In this study, we explored the capabilities of various …
10–14% of postmarket withdrawals. In this study, we explored the capabilities of various …
[HTML][HTML] Potential Application of Recombinant Snake Prothrombin Activator Ecarin in Blood Diagnostics
KN Zhao, P Masci, G Dimeski, L Johnson, M Grant… - Biomolecules, 2022 - mdpi.com
We describe here the purification and cloning of a codon-optimized form of the snake
prothrombin activator ecarin from the saw scaled viper (Echis carinatus) expressed in …
prothrombin activator ecarin from the saw scaled viper (Echis carinatus) expressed in …
Insights into Drug Cardiotoxicity from Biological and Chemical Data: The First Public Classifiers for FDA Drug-Induced Cardiotoxicity Rank
Drug-induced cardiotoxicity (DICT) is a major concern in drug development, accounting for
10–14% of postmarket withdrawals. In this study, we explored the capabilities of chemical …
10–14% of postmarket withdrawals. In this study, we explored the capabilities of chemical …
Dabigatran etexilate is efficacious in consumptive coagulopathy and pain associated with venous malformations
H Liu, L Hu, X Yang, Z Xu, H Gu, H Chen… - Journal of Vascular …, 2023 - Elsevier
Objective Consumptive coagulopathy treatment and pain management are crucial for
patients with venous malformations (VMs). Dabigatran etexilate, a non–vitamin K antagonist …
patients with venous malformations (VMs). Dabigatran etexilate, a non–vitamin K antagonist …
Insights into Drug Cardiotoxicity from Biological and Chemical Data: The First Public Classifiers for FDA Drug-Induced Cardiotoxicity Rank
O Spjuth, L Hosseini-Gerami, S Singh - 2024 - repository.cam.ac.uk
Drug-induced cardiotoxicity (DICT) is a major concern in drug development, accounting for
10–14% of postmarket withdrawals. In this study, we explored the capabilities of chemical …
10–14% of postmarket withdrawals. In this study, we explored the capabilities of chemical …
[HTML][HTML] Aktuelle Aspekte und Strategien zum Einsatz oraler Antikoagulantien und Plättchenfunktionshemmer in der Praxis
C Sucker, T Dörner - Aktuelle Rheumatologie, 2022 - thieme-connect.com
Aufgrund erhöhter venöser und arterieller Risiken und Begleiterkrankungen bei entzündlich-
rheumatischen Erkrankungen sind die Grundprinzipien der adäquaten medikamentösen …
rheumatischen Erkrankungen sind die Grundprinzipien der adäquaten medikamentösen …
Double-Enzyme Cascade Fluorescence Signal Amplification Method for Screening Coagulation Factor Fxia Inhibitor in Complex System
Y Zhan, P Hu, R Huang, X Bao, J Ning, Z Yan… - Available at SSRN … - papers.ssrn.com
The objective of this study was to establish a dual-enzyme cascade signal amplification
system for the quantitative analysis and activity screening of inhibitors targeting FXIa. In this …
system for the quantitative analysis and activity screening of inhibitors targeting FXIa. In this …