Age-related diseases are associated with increased morbidity in the past few decades and
the cost associated with the treatment of these age-related diseases exerts a substantial …

The kidneys are a pair of important organs that excretes endogenous waste and exogenous
biological agents from the body. Numerous transporters are involved in the excretion …

Hyperuricemia is a metabolic disease caused by impaired uric acid (UA) metabolism. Ellagic
acid (EA) is a natural small-molecule polyphenolic compound with known antioxidative and …

Hyperuricemia is the main cause of gout and involved in the occurrence of many other
diseases such as hyperlipidemia and hypertension correlated with metabolic disorders …

Hyperuricemia (HUA) affects human health and is involved in the pathogenesis of common
chronic diseases. Previous studies showed that Ganoderma lucidum extract lowered HUA in …

Background The correlation between periodontitis and ulcerative colitis (UC) has drawn
widespread attention recently. Fusobacterium nucleatum (F. nucleatum) as a periodontal …

As the development of hyperuricemia (HUA) and gout continues to accelerate worldwide,
there is increasing interest in the use of xanthine oxidase (XO) inhibitors as therapeutic …

Ethnopharmacological relevance Excessive serum uric acid (SUA) causes hyperuricemic
nephropathy (HN), characterized by inflammatory infiltration and tubulointerstitial fibrosis …

Hyperuricemia is the main cause of gout and involved in the occurrence of multiple
diseases, such as hypertension, metabolic disorders and chronic kidney disease. Emerging …

Mannuronate oligosaccharide (MOS) is α-D-mannuronic acid polymer with 1, 4-glycosidic
linkages that possesses beneficial biological properties. The aim of this study was to …