Abuse and misuse of pregabalin and gabapentin

KE Evoy, MD Morrison, SR Saklad - Drugs, 2017 - Springer
Background Gabapentinoid (pregabalin and gabapentin) abuse is increasingly being
reported. Objective To assess the extent of gabapentinoid abuse, characteristics of typical …

Post-operative cognitive dysfunction: an exploration of the inflammatory hypothesis and novel therapies

DR Skvarc, M Berk, LK Byrne, OM Dean, S Dodd… - Neuroscience & …, 2018 - Elsevier
Abstract Post-Operative Cognitive Dysfunction (POCD) is a highly prevalent condition with
significant clinical, social and financial impacts for patients and their communities. The …

Antiepileptic drugs for neuropathic pain and fibromyalgia‐an overview of Cochrane reviews

PJ Wiffen, S Derry, RA Moore… - Cochrane Database …, 2013 - cochranelibrary.com
Background Antiepileptic drugs have been used for treating different types of neuropathic
pain, and sometimes fibromyalgia. Our understanding of quality standards in chronic pain …

European* clinical practice recommendations on opioids for chronic noncancer pain–Part 1: Role of opioids in the management of chronic noncancer pain

W Häuser, B Morlion, KE Vowles… - … Journal of Pain, 2021 - Wiley Online Library
Background Opioid use for chronic non‐cancer pain (CNCP) is complex. In the absence of
pan‐European guidance on this issue, a position paper was commissioned by the European …

Interventions for treating pain and disability in adults with complex regional pain syndrome‐an overview of systematic reviews

NE O'Connell, BM Wand, JH McAuley… - Cochrane Database …, 2013 - cochranelibrary.com
Background There is currently no strong consensus regarding the optimal management of
complex regional pain syndrome although a multitude of interventions have been described …

[HTML][HTML] Benzodiazepine, z-drug and pregabalin prescriptions and mortality among patients in opioid maintenance treatment—a nation-wide register-based open …

T Abrahamsson, J Berge, A Öjehagen… - Drug and alcohol …, 2017 - Elsevier
Background Use of sedatives may increase risk of death in opioid users. The aim of the
study was to assess whether prescription of sedatives may be associated with mortality in …

Gabapentinoids: pharmacokinetics, pharmacodynamics and considerations for clinical practice

M Chincholkar - British journal of pain, 2020 - journals.sagepub.com
The gabapentinoids are often recommended as first-line treatments for the management of
neuropathic pain. The differing pharmacodynamic and pharmacokinetic profiles can have …

Associations between gabapentinoids and suicidal behaviour, unintentional overdoses, injuries, road traffic incidents, and violent crime: population based cohort …

Y Molero, H Larsson, BM D'Onofrio, DJ Sharp, S Fazel - bmj, 2019 - bmj.com
Objective To examine associations between gabapentinoids and adverse outcomes related
to coordination disturbances (head or body injuries, or both and road traffic incidents or …

Meta-analysis of cognitive performance in fibromyalgia

T Bell, Z Trost, MT Buelow, O Clay… - Journal of clinical and …, 2018 - Taylor & Francis
Introduction: Fibromyalgia is a condition with symptoms of pain, physical function difficulties,
and emotional problems, but is also characterized by complaints of poor cognition (often …

[HTML][HTML] Dronabinol is a safe long-term treatment option for neuropathic pain patients

S Schimrigk, M Marziniak, C Neubauer, EM Kugler… - European …, 2017 - karger.com
Abstract Treatment of neuropathic pain (NP) symptoms associated with multiple sclerosis
(MS) is frequently insufficient. Yet, cannabis is still rarely offered for treatment of pain. This …