Selectins are a group of Ca2+-dependent, transmembrane type I glycoproteins which attract
cell adhesion and migration. E-selectin is exclusively expressed in endothelial cells, and its …

The ERG (ETS-related gene) transcription factor is linked to various types of cancer,
including leukemia. However, the specific ERG domains and co-factors contributing to …

Post-transcriptional mechanisms are fundamental safeguards of progenitor cell identity and
are often dysregulated in cancer. Here, we identified regulators of P-bodies as crucial …

Background: Mitochondrial dysfunction has been implicated in the pathogenesis of
dermatomyositis (DM), a rare autoimmune disease affecting the skin and muscles. However …

Mono-allelic germline disruptions of the transcription factor GATA2 result in a propensity for
developing myelodysplastic syndrome (MDS) and acute myeloid leukemia (AML), affecting …

Aberrant expression of ecotropic viral integration site-1 (EVI1+) is associated with very poor
outcomes in acute myeloid leukemia (AML), mechanisms of which are only partially …

Hematopoietic stem cells (HSCs) and leukemia stem cells (LSCs) have robust self-renewal
potential, which is responsible for sustaining normal and malignant hematopoiesis …

The global pandemic has resulted in the common occurrence of SARS‐CoV‐2 infection in
the population. In the post‐pandemic era, it is imperative to understand the influence of …

Objective: We aimed to explore the clinical value of MDS1 and EVI1 complex locus
(MECOM) in lung adenocarcinoma (LUAD). Methods: Bioinformatics and experimental …

AML with chromosomal alterations involving 3q26 overexpresses the transcription factor
(TF) EVI1, associated with therapy refractoriness and inferior overall survival in AML …