Janus molecule I: dichotomous effects of COMT in neuropathic vs nociceptive pain modalities
SK Segall, W Maixner, I Belfer… - CNS & Neurological …, 2012 - ingentaconnect.com
The enzyme catechol-O-methyltransferase (COMT) has been shown to play a critical role in
pain perception by regulating levels of epinephrine (Epi) and norepinephrine (NE). Although …
pain perception by regulating levels of epinephrine (Epi) and norepinephrine (NE). Although …
[HTML][HTML] Analgesia induced by 2-or 100-Hz electroacupuncture in the rat tail-flick test depends on the activation of different descending pain inhibitory mechanisms
We evaluated the effectiveness of intrathecal antagonists of α1-(WB4101) and α2-(idazoxan)
adrenoceptors and serotonergic (methysergide), opioid (naloxone), muscarinic (atropine) …
adrenoceptors and serotonergic (methysergide), opioid (naloxone), muscarinic (atropine) …
Involvement of the NO/cGMP/KATP pathway in the antinociceptive effect of rosemary (Rosmarinus officinalis) essential oil in mice
V Hajhashemi, M Salimian… - Behavioural …, 2023 - journals.lww.com
Rosemary essential oil (REO) has been used for several medical purposes. Previous
studies have shown the antinociceptive effect of the oil. This study aimed to investigate the …
studies have shown the antinociceptive effect of the oil. This study aimed to investigate the …
Receptors involved in the antinociception of intrathecal melatonin in formalin test of rats
DJ Shin, CW Jeong, SH Lee, MH Yoon - Neuroscience letters, 2011 - Elsevier
The authors examined the antinocicepotive effect of melatonin in a nociceptive state and
investigated a possible interaction with adrenergic or cholinergic receptors underlying this …
investigated a possible interaction with adrenergic or cholinergic receptors underlying this …
[HTML][HTML] Antinociceptive effect of stimulating the zona incerta with glutamate in rats
The zona incerta (ZI) is a subthalamic nucleus connected to several structures, some of them
known to be involved with antinociception. The ZI itself may be involved with both …
known to be involved with antinociception. The ZI itself may be involved with both …
Roles of A-type potassium currents in tuning spike frequency and integrating synaptic transmission in noradrenergic neurons of the A7 catecholamine cell group in …
We investigated voltage-dependent K+ currents (IK) in noradrenergic (NAergic) A7 neurons.
The IK evoked consisted of A-type IK (IA), which had the characteristics of a low threshold for …
The IK evoked consisted of A-type IK (IA), which had the characteristics of a low threshold for …
Brainstem cholinergic systems
C Geula, MM Mesulam - The human nervous system. Academic …, 2011 - books.google.com
The mammalian central nervous system contains several groups of cholinergic (choline
acetyltransferase [ChAT]-positive) neurons (Geula and Mesulam, 1999). A number of these …
acetyltransferase [ChAT]-positive) neurons (Geula and Mesulam, 1999). A number of these …
Spinal mediation of descending pain inhibitory mechanisms activated by 2/100-Hz electroacupuncture in the rat tail-flick test
Electroacupuncture (EA) has been widely used for the management of chronic pain, but the
mechanism of EA-induced analgesia is not yet fully understood. The present study …
mechanism of EA-induced analgesia is not yet fully understood. The present study …
Cholinergic and glutamatergic transmission at synapses between pedunculopotine tegmental nucleus axonal terminals and A7 catecholamine cell group …
MJ Li, TW Chang, WC Hung, CY Wu, YC Luo… - …, 2016 - Elsevier
We characterized transmission from the pedunculopotine tegmental nucleus (PPTg), which
contains cholinergic and glutamatergic neurons, at synapses with noradrenergic (NAergic) …
contains cholinergic and glutamatergic neurons, at synapses with noradrenergic (NAergic) …
[PDF][PDF] Acupuncture and Related Therapies
abstract Electroacupuncture (EA) has been widely used for the management of chronic pain,
but the mechanism of EA-induced analgesia is not yet fully understood. The present study …
but the mechanism of EA-induced analgesia is not yet fully understood. The present study …