Objective 4‐n‐butylresorcinol is a competitive inhibitor of tyrosinase and has been used as
an antimelanogenic agent. However, its inhibition mechanism in intact cells is not fully …

Research on new ingredients that can prevent excessive melanin production in the skin
while considering efficacy, safety but also environmental impact is of great importance to …

Because available depigmenting agents exhibit short efficacy and serious side effects,
sericin, a waste protein from the silk industry, was hydrolyzed using Alcalase® to evaluate its …

Melasma is a common challenge in the field of pigmentary skin disorders, exerting a
significant emotional and psychosocial burden on patients. The persistent and recurring …

Depigmenting products are increasingly used to counteract skin hyperpigmentation and
related psychosocial issues. This study aimed to compare different depigmenting agents—4 …

Although melanin protects against ultraviolet radiation, its overproduction causes freckles
and senile lentigines. Recently, various biological effects of metabolites derived from marine …

The genus Scorzonera is one of the most important genera in the Asteraceae family, and
members of the genus have great potential in traditional medicine systems. In this article we …

Abstract Phenylethyl resorcinol (PER, 4-(1-phenylethyl) 1, 3-benzenediol) is a very potent
tyrosinase inhibitor with clinically proven effectiveness at already 0.5%. A major challenge of …

In this study, dihydrooxyresveratrol glucosides 3–6 were synthesized for the first time to the
best of our knowledge by the Wittig reaction and Schmidt glycosylation as key steps for the …

Postinflammatory hyperpigmentation (PIH) is a common pigmentary disorder that is
distressing to patients, particularly those with skin of color, and can be very difficult to treat …