Direct Oral Anticoagulants (DOACs) have simplified the treatment of thromboembolic
disease. In addition to their established anticoagulant effects, there are indications from …

Background: There is a plethora of real-world data on the safety and effectiveness of direct-
acting oral anticoagulants (DOACs); however, study heterogeneity has contributed to …

Vitamin K is essential for the carboxylation of the vitamin K-dependent proteins that are
responsible for the suppression of matrix calcification. The use of vitamin K antagonists …

Background The purpose of this meta-analysis was to compare efficacy and safety of direct
oral anticoagulants (DOACs) to warfarin for secondary stroke prevention among adult …

Background: Recent observational studies have compared effectiveness and safety profiles
between non-vitamin K antagonist oral anticoagulants (NOACs) and warfarin in patients with …

Aims Direct oral anticoagulants (DOAC) are progressively replacing vitamin K antagonists in
the prevention of thromboembolism in patients with atrial fibrillation. However, their real …

Abstract Background and Objective Real-life data about the use of dabigatran in patients
with non-valvular atrial fibrillation are warranted. The objective of this systematic review and …

Background Non-valvular atrial fibrillation (AF) is a common heart arrhythmia in the elderly
population. AF patients are at high-risk of ischemic strokes, but oral anticoagulant (OAC) …

The best method of anticoagulation for patients with peripheral artery disease (PAD) is still a
topic of interest for physicians. We conducted a meta-analysis to compare the effects of …

Purpose Over the last decade, the use of direct oral anticoagulants (DOACs) has strongly
increased. We aimed to describe and compare risk profiles including potential changes over …