Based on the body of evidence implicating ocular blood flow disturbances in the
pathogenesis of glaucoma, there is great interest in the investigation of the effects of …

Flow-mediated dilatation has been described mainly in peripheral conduit arteries. The goal
of this study was to examine mechanisms and functional implications of flow-mediated …

The adaptation of the brain and cerebral circulation to pregnancy are unique compared with
other organs and circulatory systems, ultimately functioning to maintain brain homeostasis …

Inhibition of angiotensin II AT1 receptors protects against stroke, reducing the cerebral blood
flow decrease in the periphery of the ischemic lesion. To clarify the mechanism …

We examined the impact of progressive hypotension with and without hypocapnia on
regional extracranial cerebral blood flow (CBF) and intracranial velocities. Participants …

Insulin resistance (IR) impairs vascular function in the peripheral and coronary circulations,
but its effects on cerebral arteries are virtually unexplored. We examined the vascular …

We examined 1) whether global cerebral blood flow (CBF) would increase across a 6-h bout
of normobaric poikilocapnic hypoxia and be mediated by a larger increase in blood flow in …

Insulin-resistance induces cerebrovascular dysfunction and increases the risk for stroke. We
investigated whether rosuvastatin (RSV), a 3-hydroxy-3-methylglutaryl coenzyme A …

High-altitude ascent imposes a unique cerebrovascular challenge due to two opposing
blood gas chemostimuli. Specifically, hypoxia causes cerebral vasodilation, whereas …

Aims The myogenic reactivity of the middle cerebral arteries (MCA) protects the brain by
altering the diameter in response to changes in lumen pressure. Large conductance …