Effect of healthy aging on cerebral blood flow, CO2 reactivity, and neurovascular coupling during exercise

D Nowak-Flück, PN Ainslie, AR Bain… - Journal of applied …, 2018 - journals.physiology.org
We sought to make the first comparisons of duplex Doppler ultrasonography-derived
measures of cerebral blood flow during exercise in young and older individuals and to …

Mild Hypercapnia Induces Vasodilation via Adenosine Triphosphate-sensitive K+Channels in Parenchymal Microvessels of the Rat Cerebral Cortex

K Nakahata, H Kinoshita, Y Hirano… - The Journal of the …, 2003 - pubs.asahq.org
Background Carbon dioxide is an important vasodilator of cerebral blood vessels. Cerebral
vasodilation mediated by adenosine triphosphate (ATP)-sensitive K+ channels has not been …

The Role of Endothelium and Nitric Oxide in Rat Pial Arteriolar Dilatory Responses to CO2 in vivo

Q Wang, DA Pelligrino, HM Koenig… - Journal of Cerebral …, 1994 - journals.sagepub.com
Using a closed cranial window system and intravital microscopy/videometry, we studied the
rat pial arteriolar (30–60 μm) responses to CO2 before and following a light/dye (L/D) …

The major cerebral arteries proximal to the Circle of Willis contribute to cerebrovascular resistance in humans

EAH Warnert, EC Hart, JE Hall… - Journal of Cerebral …, 2016 - journals.sagepub.com
Cerebral autoregulation ensures constant cerebral blood flow during periods of increased
blood pressure by increasing cerebrovascular resistance. However, whether this increase in …

Effects of arginine vasopressin on cerebral microvascular pressure

FM Faraci, WG Mayhan, PG Schmid… - American Journal of …, 1988 - journals.physiology.org
The goal of this study was to examine effects of arginine vasopressin and angiotensin on
cerebral microvascular pressure and segmental vascular resistance. We measured pressure …

Brinzolamide ophthalmic suspension: a review of its pharmacology and use in the treatment of open angle glaucoma and ocular hypertension

M Iester - Clinical Ophthalmology, 2008 - Taylor & Francis
Brinzolamide is a white powder commercially formulated as a 1% ophthalmic suspension to
reduce intraocular pressure (IOP). Pharmacologically, brinzolamide is a highly specific, non …

Extra-and intracranial blood flow regulation during the cold pressor test: influence of age

D Flück, PN Ainslie, AR Bain… - Journal of applied …, 2017 - journals.physiology.org
We determined how the extra-and intracranial circulations respond to generalized
sympathetic activation evoked by a cold pressor test (CPT) and whether this is affected by …

Retinal blood flow during dynamic exercise

A Harris, O Arend, K Bohnke, E Kroepfl, R Danis… - Graefe's archive for …, 1996 - Springer
Background: Exercise acutely lowers intraocular pressure (IOP) and raises arterial pressure.
We wondered whether the resultant increase in ocular perfusion pressure would alter retinal …

Cerebrovascular function in patients with chronic obstructive pulmonary disease: the impact of exercise training

N Lewis, JCM Gelinas, PN Ainslie… - American Journal …, 2019 - journals.physiology.org
This study examined cerebral blood flow (CBF) and its regulation before and after a short-
term periodized aerobic exercise training intervention in patients with chronic obstructive …

Role of inwardly rectifying K+ channels in K+-induced cerebral vasodilatation in vivo

S Chrissobolis, J Ziogas, YI Chu… - American Journal …, 2000 - journals.physiology.org
We tested whether activation of inwardly rectifying K+ (Kir) channels, Na+-K+-ATPase, or
nitric oxide synthase (NOS) play a role in K+-induced dilatation of the rat basilar artery in …