We have shown previously the existence of small, activity-dependent changes in intrinsic
optical properties of cortex that are useful for optical imaging of cortical functional …

A number of new imaging techniques are available to scientists to visualize the functioning
brain directly, revealing unprecedented details. These imaging techniques have provided a …

Optical imaging techniques have the potential to bring a combination of high spatial and
temporal resolution to studies of brain function. Many optical techniques require the addition …

Mitochondrial dysfunction may underlie both acute and delayed neuronal cell death
resulting from cerebral ischemia. Specifically, postischemic release of mitochondrial …

In the neocortex, neurons with similar response properties are often clustered together in
column‐like structures, giving rise to what has become known as functional architecture …

This review reports the developments in ultraviolet and light absorption spectrometry from
December 1983 through November 1985, primarily as documented in the Ultraviolet & …

The idea that electrical activity is coupled to microvascular changes is not new. Already a
century ago, Roy and Sherrington (1890) postulated that “the brain possesses an intrinsic …

This is a comment on" Increased oxygen consumption following activation of brain:
theoretical footnotes using spectroscopic data from barrel cortex." Neuroimage. 2001 Jun; …

Rapid-scanning reflectance spectrophotometry was used to evaluate the reduction-oxidation
state of cytochrome oxidase in normoxic rat brain. Reflectance spectra were recorded from …

During the last 20 years, optical imaging methods–either alone or in combination with other
recording techniques–has proven a fruitful approach to explore both the physiological and …