Worldwide, Alzheimer's disease (AD) is the most common neurodegenerative multifactorial
disease influencing the elderly population. Nowadays, several medications, among them …

Self-assembly of misfolded proteins into ordered fibrillar aggregates known as amyloid
results in various human diseases. However, more and more proteins, whether in human …

The pervasive employment of pesticides such as rotenone on a global scale represents a
substantial hazard to human health through direct exposure. Therefore, exploring the …

Curcumin faces challenges such as poor aqueous solubility and limited bioaccessibility
which limits its oral therapeutic applications. This work evaluated the complexation of …

Organophosphorus compounds are generally toxic compounds found uses in agriculture,
pharmaceutics, and other industries. These organophosphorus compounds are life …

The interaction of an important antibiotic drug, ceftazidime, with an imperative globular
protein, lysozyme (which also possesses antibacterial properties), was studied. The …

Protein fibrillation and oxidative damage are closely associated with the development of
many chronic diseases such as Alzheimer's disease, Parkinson's disease and transthyretin …

Misfolding proteins could form oligomers or amyloid fibers, which can cause a variety of
amyloid-associated diseases. Thus, the inhibition of protein misfolding and fibrillation is a …

Galangal extract (GE)-based hypouricemic functional food is under-developed due to
ambiguous quality control standard that is closely associated with action mechanisms and …

Amyloid proteins were recognized as the crucial cause of many senile diseases. In this
study, the inhibitory effects of Sennoside A (SA) and Sennoside C (SC) on amyloid …