Endocrine disrupting chemicals: exposure, effects on human health, mechanism of action, models for testing and strategies for prevention

B Yilmaz, H Terekeci, S Sandal… - Reviews in endocrine and …, 2020 - Springer
Abstract Endocrine Disrupting Chemicals (EDCs) are a global problem for environmental
and human health. They are defined as “an exogenous chemical, or mixture of chemicals …

Obesity II: establishing causal links between chemical exposures and obesity

JJ Heindel, S Howard, K Agay-Shay, JP Arrebola… - Biochemical …, 2022 - Elsevier
Obesity is a multifactorial disease with both genetic and environmental components. The
prevailing view is that obesity results from an imbalance between energy intake and …

Health and environmental effects of persistent organic pollutants

OML Alharbi, RA Khattab, I Ali - Journal of Molecular Liquids, 2018 - Elsevier
Persistent organic pollutants (POPs) are considered as the silent killers due to their bio-
accumulative and long persistent natures. These are present everywhere in our environment …

[HTML][HTML] Metabolism disrupting chemicals and metabolic disorders

JJ Heindel, B Blumberg, M Cave, R Machtinger… - Reproductive …, 2017 - Elsevier
The recent epidemics of metabolic diseases, obesity, type 2 diabetes (T2D), liver lipid
disorders and metabolic syndrome have largely been attributed to genetic background and …

Pesticides: an update of human exposure and toxicity

S Mostafalou, M Abdollahi - Archives of toxicology, 2017 - Springer
Pesticides are a family of compounds which have brought many benefits to mankind in the
agricultural, industrial, and health areas, but their toxicities in both humans and animals …

Persistent organic pollutants in food: contamination sources, health effects and detection methods

W Guo, B Pan, S Sakkiah, G Yavas, W Ge… - International journal of …, 2019 - mdpi.com
Persistent organic pollutants (POPs) present in foods have been a major concern for food
safety due to their persistence and toxic effects. To ensure food safety and protect human …

Non-monotonic dose-response relationships and endocrine disruptors: a qualitative method of assessment

F Lagarde, C Beausoleil, SM Belcher… - Environmental …, 2015 - Springer
Experimental studies investigating the effects of endocrine disruptors frequently identify
potential unconventional dose-response relationships called non-monotonic dose-response …

Metabolic syndrome and endocrine disrupting chemicals: an overview of exposure and health effects

E Haverinen, MF Fernandez, V Mustieles… - International journal of …, 2021 - mdpi.com
Increasing prevalence of metabolic syndrome (MetS) is causing a significant health burden
among the European population. Current knowledge supports the notion that endocrine …

Hormones and endocrine-disrupting chemicals: low-dose effects and nonmonotonic dose responses

LN Vandenberg, T Colborn, TB Hayes… - Endocrine …, 2012 - academic.oup.com
For decades, studies of endocrine-disrupting chemicals (EDCs) have challenged traditional
concepts in toxicology, in particular the dogma of “the dose makes the poison,” because …

Chlorinated persistent organic pollutants, obesity, and type 2 diabetes

DH Lee, M Porta, DR Jacobs Jr… - Endocrine …, 2014 - academic.oup.com
Persistent organic pollutants (POPs) are lipophilic compounds that travel with lipids and
accumulate mainly in adipose tissue. Recent human evidence links low-dose POPs to an …