Chimeric antigen receptor T (CAR-T) cell therapy achieved extraordinary achievements
results in antitumor treatments, especially against hematological malignancies, where it …

The advent of iPSCs has brought about a significant transformation in stem cell research,
opening up promising avenues for advancing cancer treatment. The formation of cancer is a …

The antitumor activity of activated CD 8+ T cells in the tumor microenvironment seems to be
limited due to their being metabolically unfit. This metabolic unfitness is closely associated …

The last decade has seen significant developments in cell therapies, based on permanently
differentiated, reprogrammed or engineered stem cells, for tendon injuries and degenerative …

Microglia are emerging as a key cell type in neurodegenerative diseases, yet human
microglia are challenging to study in vitro. We developed an in vitro cell model system …

Dendritic cells (DCs) are versatile elements of the immune system and are best known for
their unparalleled ability to initiate and modulate adaptive immune responses. During the …

Diabetes, a chronic metabolic disease, is recognized as the most frequent disorder in the
endocrine system with hyperglycemia dealing with either insulin resistance or insufficiency …

Dendritic cells (DCs) are efficient antigen-presenting cells (APCs) and potent activators of
naïve T cells. Therefore, they act as a connective ring between innate and adaptive …

Dendritic cells (DCs) excel at cross-presenting antigens, but their effectiveness as cancer
vaccine is limited. Here, we describe a vaccination approach using mesenchymal stromal …

Stem cells constitute one of the most promising tools for regenerative medicine. Thus, it
seems morally compelling to explore all the sources that might provide us with them …