Revisiting traumatic brain injury: from molecular mechanisms to therapeutic interventions

A Jarrahi, M Braun, M Ahluwalia, RV Gupta, M Wilson… - Biomedicines, 2020 - mdpi.com
Studying the complex molecular mechanisms involved in traumatic brain injury (TBI) is
crucial for developing new therapies for TBI. Current treatments for TBI are primarily focused …

Translational research in traumatic brain injury

D Laskowitz, G Grant - 2016 - books.google.com
Traumatic brain injury (TBI) remains a significant source of death and permanent disability,
contributing to nearly one-third of all injury related deaths in the United States and exacting …

Revisiting excitotoxicity in traumatic brain injury: from bench to bedside

D Baracaldo-Santamaría, DF Ariza-Salamanca… - Pharmaceutics, 2022 - mdpi.com
Traumatic brain injury (TBI) is one of the leading causes of morbidity and mortality.
Consequences vary from mild cognitive impairment to death and, no matter the severity of …

Lateral fluid percussion brain injury: a 15-year review and evaluation

HJ Thompson, J Lifshitz, N Marklund… - Journal of …, 2005 - liebertpub.com
This article comprehensively reviews the lateral fluid percussion (LFP) model of traumatic
brain injury (TBI) in small animal species with particular emphasis on its validity, clinical …

Temporal window of vulnerability to repetitive experimental concussive brain injury

L Longhi, KE Saatman, S Fujimoto, R Raghupathi… - …, 2005 - journals.lww.com
OBJECTIVE: Repetitive concussive brain injury (CBI) is associated with cognitive alterations
and increased risk of neurodegenerative disease. METHODS: To evaluate the temporal …

Diffusion MRI and the detection of alterations following traumatic brain injury

EB Hutchinson, SC Schwerin, AV Avram… - Journal of …, 2018 - Wiley Online Library
This article provides a review of brain tissue alterations that may be detectable using
diffusion magnetic resonance imaging MRI (dMRI) approaches and an overview and …

Activity-dependent neuroprotective protein snippet NAP reduces tau hyperphosphorylation and enhances learning in a novel transgenic mouse model

I Vulih-Shultzman, A Pinhasov, S Mandel… - … of Pharmacology and …, 2007 - ASPET
Activity-dependent neuroprotective protein (ADNP) differentially interacts with chromatin to
regulate essential genes. Because complete ADNP deficiency is embryonic lethal, the …

An in vitro model of traumatic brain injury utilising two-dimensional stretch of organotypic hippocampal slice cultures

B Morrison III, HL Cater, CD Benham… - Journal of neuroscience …, 2006 - Elsevier
Traumatic brain injury (TBI) is caused by rapid deformation of the brain, resulting in a
cascade of pathological events and ultimately neurodegeneration. Understanding how the …

Age‐dependent reduction of cortical contusion volume by ketones after traumatic brain injury

ML Prins, LS Fujima, DA Hovda - Journal of neuroscience …, 2005 - Wiley Online Library
Although the adult brain primarily metabolizes glucose, the evidence from the starvation
literature has demonstrated that the adult brain retains some potential to revert to ketone …

Viability and neuronal differentiation of neural stem cells encapsulated in silk fibroin hydrogel functionalized with an IKVAV peptide

W Sun, T Incitti, C Migliaresi… - Journal of tissue …, 2017 - Wiley Online Library
Abstract Three‐dimensional (3D) porous scaffolds combined with therapeutic stem cells play
vital roles in tissue engineering. The adult brain has very limited regeneration ability after …