Neuronal and glial cell number in the hippocampus after experimental traumatic brain injury: analysis by stereological estimation

MS Grady, JS Charleston, D Maris, BM Witgen… - Journal of …, 2003 - liebertpub.com
Fluid percussion (FP) brain injury causes spatial memory dysfunction in rats regardless of
injury location (midline vs. lateral). Standard histological analysis of the injured brains shows …

Alterations in hippocampal neurogenesis following traumatic brain injury in mice

R Rola, S Mizumatsu, S Otsuka, DR Morhardt… - Experimental …, 2006 - Elsevier
Clinical and experimental data show that traumatic brain injury (TBI)-induced cognitive
changes are often manifest as deficits in hippocampal-dependent functions of spatial …

A cannabidiol aminoquinone derivative activates the PP2A/B55α/HIF pathway and shows protective effects in a murine model of traumatic brain injury

C Navarrete, A García-Martín, A Correa-Sáez… - Journal of …, 2022 - Springer
Background Traumatic brain injury (TBI) is characterized by a primary mechanical injury and
a secondary injury associated with neuroinflammation, blood–brain barrier (BBB) disruption …

[HTML][HTML] Glucose metabolism: A link between traumatic brain injury and Alzheimer's disease

XJ Xu, MS Yang, B Zhang, F Niu, JQ Dong… - Chinese journal of …, 2021 - Elsevier
Traumatic brain injury (TBI), a growing public health problem, is a leading cause of death
and disability worldwide, although its prevention measures and clinical cares are …

Genetic deletion of Krüppel-like factor 11 aggravates traumatic brain injury

C Zhou, P Sun, MH Hamblin, KJ Yin - Journal of Neuroinflammation, 2022 - Springer
Background The long-term functional recovery of traumatic brain injury (TBI) is hampered by
pathological events, such as parenchymal neuroinflammation, neuronal death, and white …

Comparison of behavioral deficits and acute neuronal degeneration in rat lateral fluid percussion and weight-drop brain injury models

TM Hallam, CL Floyd, MM Folkerts, LL Lee… - Journal of …, 2004 - liebertpub.com
The behavioral and histological effects of the lateral fluid percussion (LFP) brain injury
model were compared with the weight drop impact-acceleration model with 10 min of …

Synaptogenesis in the hippocampal CA1 field following traumatic brain injury

SW Scheff, DA Price, RR Hicks, SA Baldwin… - Journal of …, 2005 - liebertpub.com
Traumatic brain injury (TBI) results in both acute and chronic disruption of cognitive ability
that may be mediated through a disruption of hippocampal circuitry. Experimental models of …

Early loss of astrocytes after experimental traumatic brain injury

X Zhao, A Ahram, RF Berman, JP Muizelaar, BG Lyeth - Glia, 2003 - Wiley Online Library
Neuronal‐glial interactions are important for normal brain function and contribute to the
maintenance of the brain's extracellular environment. Damage to glial cells following …

Immuno-suppressive hydrogels enhance allogeneic MSC survival after transplantation in the injured brain

M Alvarado-Velez, SF Enam, N Mehta, JG Lyon… - Biomaterials, 2021 - Elsevier
Traumatic brain injury (TBI) triggers multiple biochemical and cellular processes that
exacerbate brain tissue damage through a secondary injury. Therapies that prevent or limit …

Pre-clinical testing of therapies for traumatic brain injury

DS DeWitt, BE Hawkins, CE Dixon… - Journal of …, 2018 - liebertpub.com
Despite the large number of promising neuroprotective agents identified in experimental
traumatic brain injury (TBI) studies, none has yet shown meaningful improvements in long …