How and when should we monitor chimerism after allogeneic stem cell transplantation?

P Bader, D Niethammer, A Willasch… - Bone marrow …, 2005 - nature.com
Chimerism analysis has become an important tool for the peri-transplant surveillance of
engraftment. It offers the possibility to realize impending graft rejection and can serve as an …

[HTML][HTML] Treatment of AML relapse after allo-HCT

JA Webster, L Luznik, I Gojo - Frontiers in Oncology, 2021 - frontiersin.org
With advances in allogeneic hematopoietic stem cell transplant (allo-HCT), disease relapse
has replaced transplant-related mortality as the primary cause of treatment failure for …

[HTML][HTML] Standardizing definitions of hematopoietic recovery, graft rejection, graft failure, poor graft function, and donor chimerism in allogeneic hematopoietic cell …

MA Kharfan-Dabaja, A Kumar, E Ayala, M Aljurf… - … and cellular therapy, 2021 - Elsevier
Allogeneic hematopoietic cell transplantation (allo-HCT) is potentially curative for certain
hematologic malignancies and nonmalignant diseases. The field of allo-HCT has witnessed …

[PDF][PDF] Prognostic value of minimal residual disease quantification before allogeneic stem-cell transplantation in relapsed childhood acute lymphoblastic leukemia: the …

P Bader, H Kreyenberg, GHR Henze… - Journal of Clinical …, 2009 - researchgate.net
Purpose Minimal residual disease (MRD) before allogeneic stem-cell transplantation was
shown to predict outcome in children with relapsed acute lymphoblastic leukemia (ALL) in …

Quantitative assessment of hematopoietic chimerism after bone marrow transplantation by real-time quantitative polymerase chain reaction

M Alizadeh, M Bernard, B Danic… - Blood, The Journal …, 2002 - ashpublications.org
We have developed a real-time quantitative polymerase chain reaction (PCR) assay using
TaqMan technology (Applied Biosystems, Foster City, CA) for monitoring donor cell …

[PDF][PDF] Increasing mixed chimerism is an important prognostic factor for unfavorable outcome in children with acute lymphoblastic leukemia after allogeneic stem-cell …

P Bader, H Kreyenberg, W Hoelle… - Journal of clinical …, 2004 - researchgate.net
Purpose We recently reported that children with acute leukemias who show increasing
mixed chimerism (MC) after allogeneic stem-cell transplantation have a significantly …

Megadose transplantation of purified peripheral blood CD34+ progenitor cells from HLA-mismatched parental donors in children

R Handgretinger, T Klingebiel, P Lang… - Bone marrow …, 2001 - nature.com
We performed HLA-mismatched stem cell transplantation with megadoses of purified
positively selected mobilized peripheral blood CD34+ progenitor cells (PBPC) from related …

Sequential monitoring of chimerism and detection of minimal residual disease after allogeneic blood stem cell transplantation (BSCT) using multiplex PCR …

C Thiede, M Bornhäuser, U Oelschlägel, C Brendel… - Leukemia, 2001 - nature.com
Sequential analysis of chimerism after allogeneic blood stem cell transplantation (BSCT)
has been shown to be predictive for graft failure and relapse. We have explored the impact …

Significance of chimerism in hematopoietic stem cell transplantation: new variations on an old theme

F Khan, A Agarwal, S Agrawal - Bone marrow transplantation, 2004 - nature.com
The main goal of post-transplantation monitoring in hematopoietic stem cell transplantation
(HSCT) is to predict negative events, such as disease relapse, graft rejection and graft …

[HTML][HTML] Haploidentical allogeneic hematopoietic cell transplantation in adults using CD3/CD19 depletion and reduced intensity conditioning: a phase II study

B Federmann, M Bornhauser, C Meisner… - …, 2012 - ncbi.nlm.nih.gov
Haploidentical allogeneic hematopoietic cell transplantation in adults using CD3/CD19
depletion and reduced intensity conditioning: a phase II study - PMC Back to Top Skip to main …