Apathy and anhedonia are common syndromes of motivation that are associated with a wide
range of brain disorders and have no established therapies. Research using animal models …

Nucleus accumbens dopamine is known to play a role in motivational processes, and
dysfunctions of mesolimbic dopamine may contribute to motivational symptoms of …

Nearly 40 years of research on the function of the nucleus accumbens (NAc) has provided a
wealth of information on its contributions to behavior but has also yielded controversies and …

Anhedonia, or markedly diminished interest or pleasure, is a hallmark symptom of major
depression, schizophrenia and other neuropsychiatric disorders. Over the past three …

Motivation has been defined as the process that allows organisms to regulate their internal
and external environment, and control the probability, proximity and availability of stimuli. As …

This article reviews and synthesizes research on reward processing in schizophrenia, which
has begun to provide important insights into the cognitive and neural mechanisms …

What roles do mesolimbic and neostriatal dopamine systems play in reward? Do they
mediate the hedonic impact of rewarding stimuli? Do they mediate hedonic reward learning …

The hypothesis that dopamine is important for reward has been proposed in a number of
forms, each of which has been challenged. Normally, rewarding stimuli such as food, water …

Since its first edition, An Introduction to Theories of Learning has provided a uniquely
sweeping review of the major learning theories from the 20th century that profoundly …

A markedly reduced interest or pleasure in activities previously considered pleasurable is a
main symptom in mood disorder and psychosis and is often present in other psychiatric …