Deprescribing in the older patient: a narrative review of challenges and solutions
H Wu, L Kouladjian O'Donnell, K Fujita… - … journal of general …, 2021 - Taylor & Francis
Polypharmacy is a major challenge in healthcare for older people, and is associated with
increased risks of adverse outcomes, such as delirium, falls, frailty, cognitive impairment and …
increased risks of adverse outcomes, such as delirium, falls, frailty, cognitive impairment and …
[HTML][HTML] Deprescribing medicines in older people living with multimorbidity and polypharmacy: the TAILOR evidence synthesis.
J Reeve, M Maden, R Hill, A Turk… - Health Technology …, 2022 - ncbi.nlm.nih.gov
BACKGROUND Tackling problematic polypharmacy requires tailoring the use of medicines
to individual needs and circumstances. This may involve stopping medicines (deprescribing) …
to individual needs and circumstances. This may involve stopping medicines (deprescribing) …
Barriers and enablers of healthcare providers to deprescribe cardiometabolic medication in older patients: a focus group study
J Abou, S Crutzen, V Tromp, M Heringa, R Van Marum… - Drugs & aging, 2022 - Springer
Introduction Benefits and risks of preventive medication change over time for ageing patients
and deprescribing of medication may be needed. Deprescribing of cardiovascular and …
and deprescribing of medication may be needed. Deprescribing of cardiovascular and …
[HTML][HTML] Artificial intelligence-supported web application design and development for reducing polypharmacy side effects and supporting rational drug use in geriatric …
Introduction: The main complications of polypharmacy, which is known as the simultaneous
use of more than five drugs, are potentially inappropriate medicines (PIMs), drug-drug, and …
use of more than five drugs, are potentially inappropriate medicines (PIMs), drug-drug, and …
How willing are patients or their caregivers to deprescribe: a systematic review and meta-analysis
Background Polypharmacy is associated with the increased use of potentially inappropriate
medications, where the risks of medicine use outweigh its benefits. Stopping medicines …
medications, where the risks of medicine use outweigh its benefits. Stopping medicines …
Polypharmacy and deprescribing in older adults
W Thompson, EG McDonald - Annual Review of Medicine, 2024 - annualreviews.org
Older adults commonly end up on many medications. Deprescribing is an important part of
individualizing care for older adults. It is an opportunity to discuss treatment options and …
individualizing care for older adults. It is an opportunity to discuss treatment options and …
Effectiveness of bundled hyperpolypharmacy deprescribing compared with usual care among older adults: a randomized clinical trial
LJ Herrinton, K Lo, M Alavi, SE Alexeeff… - JAMA Network …, 2023 - jamanetwork.com
Importance Older patients using many prescription drugs (hyperpolypharmacy) may be at
increased risk of adverse drug effects. Objective To test the effectiveness and safety of a …
increased risk of adverse drug effects. Objective To test the effectiveness and safety of a …
“Kind of blurry”: Deciphering clues to prevent, investigate and manage prescribing cascades
B Farrell, E Galley, L Jeffs, P Howell, LM McCarthy - PloS one, 2022 - journals.plos.org
Background Prescribing cascades, where a medication is used to treat the side effect of
another medication, contribute to polypharmacy and related morbidity. Little is known about …
another medication, contribute to polypharmacy and related morbidity. Little is known about …
Barriers and facilitators of successful deprescribing as described by older patients living with frailty, their informal carers and clinicians: a qualitative interview study
Objective To explore the barriers/facilitators to deprescribing in primary care in England from
the perspectives of clinicians, patients living with frailty who reside at home, and their …
the perspectives of clinicians, patients living with frailty who reside at home, and their …