Classical pharmaceutical research and development relies on the identification and
validation of i) membranepermeable small molecules or ii) extracellular targets that are able …

Glycosaminoglycans (GAGs) contribute to the cellular uptake of cationic cell-penetrating
peptides (CPPs). However, molecular details about the contributions of GAGs in CPP …

Short cationic oligomers, including arginine‐rich peptides and analogous β‐amino acid
oligomers (“β‐peptides”), can enter the cytoplasm and nucleus of a living cell from the …

The aim of the study was to test the hypothesis that the biophysical interactions of the trans-
activating transcriptor (TAT) peptide-conjugated nanoparticles (NPs) with a model cell …

We have developed nanoparticles based on Murine Leukemia Virus virus-like-particles
(VLPs) that efficiently deliver therapeutic bioactive proteins in their native state into target …

Saliva contains hundreds of small proline-rich peptides most of which derive from the post-
translational and post-secretory processing of the acidic and basic salivary proline-rich …

As mitochondria are potential therapeutic targeting sites for the treatment of human
diseases, delivering cytotoxic drugs, antioxidants, and imaging molecules to mitochondria …

Cell‐penetrating peptides (CPPs) are commonly defined by their shared ability to be
internalized into eukaryotic cells, without inducing permanent membrane damage, and to …

The inability to transduce cellular membranes is a limitation of current magnetic resonance
imaging probes used in biologic and clinical settings. This constraint confines contrast …

Abstract Compositions, methods, strategies, kits, and systems for the supercharged protein-
mediated delivery of functional effector proteins into cells in vivo, ex vivo, or in vitro are …