In this brief report, we offer a concise overview on current cancer epidemiology garnered
from the official databases of World Health Organization and American Cancer Society and …

Systemic chemotherapy remains the backbone of many cancer treatments. Due to its
untargeted nature and the severe side effects it can cause, numerous nanomedicine …

Abstract Cisplatin or (SP-4-2)-diamminedichloridoplatinum (II) is one of the most potential
and widely used drugs for the treatment of various solid cancers such as testicular, ovarian …

The emergence of immunotherapy has been an astounding breakthrough in cancer
treatments. In particular, immune checkpoint inhibitors, targeting PD-1 and CTLA-4, have …

Multiple cancer immunotherapies including chimeric antigen receptor T cell and immune
checkpoint inhibitors (ICIs) have been successfully developed to treat various cancers by …

Patient-derived xenograft (PDX) models are created by engraftment of patient tumor tissues
into immunocompetent mice. Since a PDX model retains the characteristics of the primary …

Throughout the United States, cancer remains the second leading cause of death.
Traditional treatments induce significant medical toxic effects and unpleasant adverse …

Loss of fertility is a major concern for female reproductive-age cancer survivors, since a
common side-effect of conventional cytotoxic cancer therapies is permanent damage to the …

Incapacitated immune system is a characteristic hallmark of solid tumors. Immune system
within a tumor undergoes an imbalance in cellular dispersion and functionality. Effector cells …

The immune system takes part in most physiological and pathological processes of the
body, including the occurrence and development of cancer. Immunotherapy provides a …