5-HT receptors expressed throughout the human body are targets for established
therapeutics and various drugs in development. Their diversity of structure and function …

Since our review of central 5-HT receptors and their function twenty years ago, no new 5-HT
receptor has been discovered and there is little evidence that this situation will change in the …

Objective To investigate the effect of second‐generation antipsychotics on cognitive function
in patients diagnosed with schizophrenia or schizoaffective disorder. Method Multiple …

We have previously shown that prebiotics (dietary fibres that augment the growth of
indigenous beneficial gut bacteria) such as Bimuno™ galacto-oligosaccharides (B-GOS®) …

Serotonin (5-HT) is an important player in decision making. Serotonergic antidepressant,
anxiolytic and antipsychotic drugs are extensively used in the treatment of neuropsychiatric …

It has been known for several decades that serotonergic neurotransmission is a key
regulator of cognitive function, mood, and sleep. Yet with the relatively recent discoveries of …

The constitutive activity of different serotonin receptors (5-HTRs) toward intracellular
signaling pathways has been proposed to have physiological and pathological importance …

Objective To review the evidence that agents which preferentially affect serotonin (5-HT)
attenuate the ability of N-methyl-D-aspartate (NMDA) receptor non-competitive antagonists …

Antagonism of the 5-HT 6 receptor is a promising approach for the symptomatic treatment of
Alzheimer's disease (AD). There is compelling preclinical evidence for the procognitive …

Given its predominant expression in the central nervous system (CNS), 5-hydroxytryptamine
(5-HT: serotonin) subtype 6 receptor (5-HT6R) has been considered as a valuable target for …