[HTML][HTML] Sterilization and disinfection methods for decellularized matrix materials: Review, consideration and proposal

M Tao, T Ao, X Mao, X Yan, R Javed, W Hou, Y Wang… - Bioactive materials, 2021 - Elsevier
Sterilization is the process of killing all microorganisms, while disinfection is the process of
killing or removing all kinds of pathogenic microorganisms except bacterial spores …

Engineering organs

A Atala - Current opinion in biotechnology, 2009 - Elsevier
Applications of regenerative medicine technology may offer novel therapies for patients with
injuries, end-stage organ failure, or other clinical problems. Currently, patients suffering from …

Human urine-derived stem cells seeded in a modified 3D porous small intestinal submucosa scaffold for urethral tissue engineering

S Wu, Y Liu, S Bharadwaj, A Atala, Y Zhang - Biomaterials, 2011 - Elsevier
The goal of this study was to determine whether urothelial cells (UC) and smooth muscle
cells (SMC) derived from the differentiation of urine-derived stem cells (USC) could be used …

[HTML][HTML] Tissue engineering and regenerative medicine in pediatric urology: urethral and urinary bladder reconstruction

M Casarin, A Morlacco, F Dal Moro - International Journal of Molecular …, 2022 - mdpi.com
In the case of pediatric urology there are several congenital conditions, such as
hypospadias and neurogenic bladder, which affect, respectively, the urethra and the urinary …

[HTML][HTML] Tissue engineering of urinary bladder and urethra: advances from bench to patients

H Orabi, S Bouhout, A Morissette… - The Scientific World …, 2013 - hindawi.com
Urinary tract is subjected to many varieties of pathologies since birth including congenital
anomalies, trauma, inflammatory lesions, and malignancy. These diseases necessitate the …

Cell-seeded tubularized scaffolds for reconstruction of long urethral defects: a preclinical study

H Orabi, T AbouShwareb, Y Zhang, JJ Yoo, A Atala - European urology, 2013 - Elsevier
BACKGROUND: The treatment options for patients requiring repair of a long segment of the
urethra are limited by the availability of autologous tissues. We previously reported that …

[HTML][HTML] Urethral reconstruction with autologous urine-derived stem cells seeded in three-dimensional porous small intestinal submucosa in a rabbit model

Y Liu, W Ma, B Liu, Y Wang, J Chu, G Xiong… - Stem cell research & …, 2017 - Springer
Background Urethral reconstruction is one of the great surgical challenges for urologists. A
cell-based tissue-engineered urethra may be an alternative for patients who have …

Bladder acellular matrix and its application in bladder augmentation

L Song, SV Murphy, B Yang, Y Xu… - … Engineering Part B …, 2014 - liebertpub.com
Over the last few decades, both synthetic and natural materials have been utilized to
develop bladder substitutes. Most attempts have not been successful because of …

Bladder reconstruction with adipose-derived stem cell-seeded bladder acellular matrix grafts improve morphology composition

W Zhu, Y Xu, C Feng, Q Fu, L Song, L Cui - World Journal of Urology, 2010 - Springer
Purpose To assess the feasibility of seeding adipose-derived stem cells (ADSCs) onto
bladder acellular matrix grafts (BAMGs) for bladder reconstruction in a rabbit model …

[HTML][HTML] Fabrication of tissue-engineered bionic urethra using cell sheet technology and labeling by ultrasmall superparamagnetic iron oxide for full-thickness urethral …

S Zhou, R Yang, Q Zou, K Zhang, T Yin, W Zhao… - Theranostics, 2017 - ncbi.nlm.nih.gov
Urethral strictures remain a reconstructive challenge, due to less than satisfactory outcomes
and high incidence of stricture recurrence. An “ideal” urethral reconstruction should …