Neuroinflammation and microglia in glaucoma: time for a paradigm shift
Glaucoma is a complex neurodegenerative disease with many clinical subtypes. Some of its
rare forms include pigmentary glaucoma, uveitic glaucoma and congenital glaucoma. While …
rare forms include pigmentary glaucoma, uveitic glaucoma and congenital glaucoma. While …
Retinal ganglion cells: Energetics, compartmentation, axonal transport, cytoskeletons and vulnerability
DY Yu, SJ Cringle, C Balaratnasingam… - Progress in retinal and …, 2013 - Elsevier
Retinal ganglion cells (RGCs) are specialized projection neurons that relay an immense
amount of visual information from the retina to the brain. RGC signal inputs are collected by …
amount of visual information from the retina to the brain. RGC signal inputs are collected by …
Commensal microflora-induced T cell responses mediate progressive neurodegeneration in glaucoma
Glaucoma is the most prevalent neurodegenerative disease and a leading cause of
blindness worldwide. The mechanisms causing glaucomatous neurodegeneration are not …
blindness worldwide. The mechanisms causing glaucomatous neurodegeneration are not …
Neuroinflammation in primary open-angle glaucoma
S Vernazza, S Tirendi, AM Bassi, CE Traverso… - Journal of clinical …, 2020 - mdpi.com
Primary open-angle glaucoma (POAG) is the second leading cause of irreversible blindness
worldwide. Increasing evidence suggests oxidative damage and immune response defects …
worldwide. Increasing evidence suggests oxidative damage and immune response defects …
Neuroglobin: From structure to function in health and disease
P Ascenzi, A di Masi, L Leboffe, M Fiocchetti… - Molecular aspects of …, 2016 - Elsevier
In 2000, the third member of the globin family was discovered in human and mouse brain
and named neuroglobin (Ngb). Ngb is a monomeric 3/3 globin structurally similar to …
and named neuroglobin (Ngb). Ngb is a monomeric 3/3 globin structurally similar to …
Review of rodent hypertensive glaucoma models
Glaucoma is a neurodegenerative disease characterized by the progressive loss of retinal
ganglion cells (RGC s). Elevated intraocular pressure (IOP) is a primary risk factor for the …
ganglion cells (RGC s). Elevated intraocular pressure (IOP) is a primary risk factor for the …
Neuroprotection in glaucoma: recent advances and clinical translation
Intraocular pressure (IOP) reduction is currently the only evidence‐based treatment strategy
for glaucoma. However, IOP control in some individuals is challenging. Despite optimal …
for glaucoma. However, IOP control in some individuals is challenging. Despite optimal …
Age and intraocular pressure in murine experimental glaucoma
J Di Pierdomenico, DCM Henderson… - Progress in Retinal and …, 2022 - Elsevier
Age and intraocular pressure (IOP) are the two most important risk factors for the
development and progression of open-angle glaucoma. While IOP is commonly considered …
development and progression of open-angle glaucoma. While IOP is commonly considered …
Neuroglobin, clues to function and mechanism
C Exertier, LC Montemiglio, I Freda, E Gugole… - Molecular Aspects of …, 2022 - Elsevier
Neuroglobin is expressed in vertebrate brain and belongs to a branch of the globin family
that diverged early in evolution. Sequence conservation and presence in nervous cells of …
that diverged early in evolution. Sequence conservation and presence in nervous cells of …
Effect of mindfulness meditation on intraocular pressure and trabecular meshwork gene expression: A randomized controlled trial
T Dada, N Bhai, N Midha, J Shakrawal, M Kumar… - American Journal of …, 2021 - Elsevier
Purpose To evaluate the effect of mindfulness meditation (MM) on intraocular pressure (IOP)
and trabecular meshwork (TM) gene expression in patients with medically uncontrolled …
and trabecular meshwork (TM) gene expression in patients with medically uncontrolled …