A fundamental goal in plant biology is to identify and understand the variation underlying
plants' adaptation to their environment. Climate change has given new urgency to this goal …

The growing world population, in combination with the anticipated effects of climate change,
is pressuring food security. Plants display an impressive arsenal of cellular mechanisms …

Studying the plasma proteome as the intermediate layer between the genome and the
phenome has the potential to identify new disease processes. Here, we conducted a cis …

Wide variation in amenability to transformation and regeneration (TR) among many plant
species and genotypes presents a challenge to the use of genetic engineering in research …

The identification of genomic loci that are associated with osteoarthritis (OA) has provided a
starting point for understanding how genetic variation activates catabolic processes in the …

Chromatin accessibility sequencing has been widely used for uncovering genetic regulatory
mechanisms and inferring gene regulatory networks. However, effectively integrating large …

Genome-wide association studies (GWAS) have mapped over 90% of disease-or trait-
associated variants within the non-coding genome, like cis-regulatory elements (CREs). Non …

Cardiovascular disease is the leading cause of death worldwide, and it commonly results
from atherosclerotic plaque progression. One of the increasingly recognized drivers of …

Genome-wide association studies (GWASs) provide a key foundation for elucidating the
genetic underpinnings of common polygenic diseases. However, these studies have …

Genomic aberrations are a critical impediment for the safe medical use of iPSCs and their
origin and developmental mechanisms remain unknown. Here we find through WGS …