Pancreatic cancer is the seventh leading cause of cancer-related deaths worldwide.
However, its toll is higher in more developed countries. Reasons for vast differences in …

Free radical damage is linked to formation of many degenerative diseases, including cancer,
cardiovascular disease, cataracts, and aging. Excessive reactive oxygen species (ROS) …

Despite its very low level in humans, selenium plays an important and unique role among
the (semi) metal trace essential elements because it is the only one for which incorporation …

Abstract The American Cancer Society (ACS) publishes Nutrition and Physical Activity
Guidelines to serve as a foundation for its communication, policy, and community strategies …

This review covers current knowledge of selenium in the environment, dietary intakes,
metabolism and status, functions in the body, thyroid hormone metabolism, antioxidant …

Free radicals and oxidants play a dual role as both toxic and beneficial compounds, since
they can be either harmful or helpful to the body. They are produced either from normal cell …

Various nutritional, behavioral, and pharmacological interventions have been previously
shown to extend life span in diverse model organisms, including Saccharomyces cerevisiae …

Recent evidence suggests that calorie restriction and specifically reduced glucose
metabolism induces mitochondrial metabolism to extend life span in various model …

Reactive oxygen species (ROS) are widely believed to cause or aggravate several human
pathologies such as neurodegenerative diseases, cancer, stroke and many other ailments …

Glutathione (GSH) and bilirubin are prominent endogenous antioxidant cytoprotectants.
Despite tissue levels that are thousands of times lower than GSH, bilirubin is effective …