PVT1 lncRNA in lung cancer: A key player in tumorigenesis and therapeutic opportunities
The lncRNA PVT1 has emerged as a pivotal component in the intricate landscape of cancer
pathogenesis, particularly in lung cancer. PVT1, situated in the 8q24 chromosomal region …
pathogenesis, particularly in lung cancer. PVT1, situated in the 8q24 chromosomal region …
From carcinogenesis to therapeutic avenues: lncRNAs and mTOR crosstalk in lung cancer
Long non-coding RNAs (lncRNAs) have been demonstrated to have a crucial function in the
modulation of the activity of genes, impacting a variety of homeostatic processes involving …
modulation of the activity of genes, impacting a variety of homeostatic processes involving …
18-β-Glycyrrhetinic acid encapsulated PLGA nanoparticles attenuate lung cancer proliferation and migration
KR Paudel, MSB Mohamad, G De Rubis… - Journal of Drug Delivery …, 2024 - Elsevier
Conventional treatment methods to treat lung cancer include radiation therapy,
chemotherapy, and immunotherapy. However, they cause severe adverse effects and …
chemotherapy, and immunotherapy. However, they cause severe adverse effects and …
[HTML][HTML] Cellular senescence in lung cancer: Molecular mechanisms and therapeutic interventions
Lung cancer stands as the primary contributor to cancer-related fatalities worldwide,
affecting both genders. Two primary types exist where non-small cell lung cancer (NSCLC) …
affecting both genders. Two primary types exist where non-small cell lung cancer (NSCLC) …
Fecal microbiome extract downregulates the expression of key proteins at the interface between airway remodelling and lung cancer pathogenesis in vitro
Lung cancer (LC) is the leading cause of cancer-related mortality, and it is caused by many
factors including cigarette smoking. Despite numerous treatment strategies for LC, its five …
factors including cigarette smoking. Despite numerous treatment strategies for LC, its five …
[HTML][HTML] Liposomal curcumin inhibits cigarette smoke induced senescence and inflammation in human bronchial epithelial cells
S Kokkinis, G De Rubis, KR Paudel, VK Patel… - … -Research and Practice, 2024 - Elsevier
Curcumin, the principal curcuminoid of turmeric (Curcuma longa extract), is very well known
for its multiple biological therapeutic activities, particularly its anti-inflammatory and …
for its multiple biological therapeutic activities, particularly its anti-inflammatory and …
[HTML][HTML] Curcumin-loaded liposomes modulating the synergistic role of EpCAM and estrogen receptor alpha in lung cancer management
Lung cancer (LC) remains a leading cause of cancer-related mortality worldwide,
necessitating the exploration of innovative therapeutic strategies. This study delves into the …
necessitating the exploration of innovative therapeutic strategies. This study delves into the …
[HTML][HTML] 18-β-glycyrrhetinic acid-loaded polymeric nanoparticles attenuate cigarette smoke-induced markers of impaired antiviral response in vitro
G De Rubis, KR Paudel, S Yeung, S Mohamad… - … -Research and Practice, 2024 - Elsevier
Tobacco smoking is a leading cause of preventable mortality, and it is the major contributor
to diseases such as COPD and lung cancer. Cigarette smoke compromises the pulmonary …
to diseases such as COPD and lung cancer. Cigarette smoke compromises the pulmonary …
Plant-based therapeutics for chronic obstructive pulmonary diseases: Nanoformulation strategies to overcome delivery challenges
Chronic obstructive pulmonary disease (COPD) is a widespread global health problem
marked by increasing airflow limitation and chronic airway inflammation. Conventional …
marked by increasing airflow limitation and chronic airway inflammation. Conventional …
Ribavirin attenuates carcinogenesis by downregulating IL-6 and IL-8 in vitro in human lung adenocarcinoma
Lung cancer is one of the leading causes of death worldwide, whereby the major
contributing factors are cigarette smoking and exposure to environmental pollutants. Despite …
contributing factors are cigarette smoking and exposure to environmental pollutants. Despite …