[HTML][HTML] Exosomes: Small vesicles with big roles in cancer, vaccine development, and therapeutics

A Thakur, DC Parra, P Motallebnejad, M Brocchi… - Bioactive materials, 2022 - Elsevier
Cancer is a deadly disease that is globally and consistently one of the leading causes of
mortality every year. Despite the availability of chemotherapy, radiotherapy, immunotherapy …

Towards microfluidic-based exosome isolation and detection for tumor therapy

J Wang, P Ma, DH Kim, BF Liu, U Demirci - Nano Today, 2021 - Elsevier
Exosomes are a class of cell-secreted, nano-sized extracellular vesicles with a bilayer
membrane structure of 30–150 nm in diameter. Their discovery and application have …

A comprehensive review on factors influences biogenesis, functions, therapeutic and clinical implications of exosomes

S Gurunathan, MH Kang, JH Kim - International journal of …, 2021 - Taylor & Francis
Exosomes are nanoscale-sized membrane vesicles secreted by almost all cell types into the
extracellular environment upon fusion of multivesicular bodies and plasma membrane …

[HTML][HTML] Exosomes engineering and their roles as therapy delivery tools, therapeutic targets, and biomarkers

N Kučuk, M Primožič, Ž Knez, M Leitgeb - International journal of …, 2021 - mdpi.com
Exosomes are becoming increasingly important therapeutic biomaterials for use in a variety
of therapeutic applications due to their unique characteristics, especially due to the …

[HTML][HTML] Exosomes: cell-derived nanoplatforms for the delivery of cancer therapeutics

H Kim, EH Kim, G Kwak, SG Chi, SH Kim… - International journal of …, 2020 - mdpi.com
Exosomes are cell-secreted nanovesicles that naturally contain biomolecular cargoes such
as lipids, proteins, and nucleic acids. Exosomes mediate intercellular communication …

[HTML][HTML] The potential use of mesenchymal stem cells and their derived exosomes for orthopedic diseases treatment

K Malekpour, A Hazrati, M Zahar, A Markov… - Stem cell reviews and …, 2022 - Springer
Musculoskeletal disorders (MSDs) are conditions that can affect muscles, bones, and joints.
These disorders are very painful and severely limit patients' mobility and are more common …

A guide to mass spectrometric analysis of extracellular vesicle proteins for biomarker discovery

I Jalaludin, DM Lubman, J Kim - Mass Spectrometry Reviews, 2023 - Wiley Online Library
Exosomes (small extracellular vesicles) in living organisms play an important role in
processes such as cell proliferation or intercellular communication. Recently, exosomes …

Advances of nanomedicines in breast cancer metastasis treatment targeting different metastatic stages

W Yu, C Hu, H Gao - Advanced Drug Delivery Reviews, 2021 - Elsevier
Breast cancer is the most common tumor in women, and the metastasis further increases the
malignancy with extremely high mortality. However, there is almost no effective method in …

[HTML][HTML] Engineered exosomes for tumor-targeted drug delivery: a focus on genetic and chemical functionalization

A Akbari, F Nazari-Khanamiri, M Ahmadi, M Shoaran… - Pharmaceutics, 2022 - mdpi.com
Cancer is the main cause of death worldwide. The limitations in traditional cancer therapies
provoked the advance and use of several nanotechnologies for more effective and nontoxic …

[HTML][HTML] Extracellular vesicles as innovative tool for diagnosis, regeneration and protection against neurological damage

P Andjus, M Kosanović, K Milićević, M Gautam… - International journal of …, 2020 - mdpi.com
Extracellular vesicles (EVs) have recently attracted a great deal of interest as they may
represent a new biosignaling paradigm. According to the mode of biogenesis, size and …