Simple Summary Epithelial ovarian cancer is one of the most lethal cancers in women and is
typically diagnosed at an advanced-stage. Historically, primary tumor reductive surgery was …

High-grade serous ovarian cancer (HGSOC) is the most frequent and aggressive type of
epithelial ovarian cancer, with high recurrence rate and chemoresistance being the main …

Ovarian cancer (OC) is a malignant tumor that seriously threatens women's health. Due to
the difficulty of early diagnosis, most patients exhibit advanced disease or peritoneal …

Female breast cancer, ovarian cancer, cervical cancer, and endometrial cancer are the most
common tumors and the most common causes of cancer-related mortality worldwide in …

Currently, for ovarian cancer, which has the highest mortality rate among all gynecological
cancers, the standard treatment protocol is initial tumor cytoreductive surgery followed by …

Ovarian cancer is the most lethal gynecologic malignancy with a stubborn mortality rate of~
65%. The persistent failure of multiline chemotherapy, and significant tumor heterogeneity …

Objective: Neoadjuvant chemotherapy (NACT) is one kind of treatment for advanced stage
ovarian cancer patients. However, due to the nature of tumor heterogeneity, the patients' …

The high rate of ovarian cancer recurrence and chemoresistance necessitates further
research into how chemotherapy affects the tumor immune microenvironment (TIME). While …

Background Ovarian cancer (OC) is a heterogeneous gynecological malignancy with a poor
prognosis as the majority of patients are diagnosed at an advanced stage. Neoadjuvant …

BRCA1 and BRCA2 are multi-functional proteins and key factors for maintaining genomic
stability through their roles in DNA double strand break repair by homologous …