Advances in immunotherapy for cervical cancer
JF Grau-Bejar, C Garcia-Duran… - Therapeutic …, 2023 - journals.sagepub.com
Cervical cancer still represents a major public health problem, being the fourth most
common cancer in incidence and mortality in women worldwide. These figures are …
common cancer in incidence and mortality in women worldwide. These figures are …
Nanocarriers: a reliable tool for the delivery of anticancer drugs
Nanomedicines have gained popularity due to their potential therapeutic applications,
especially cancer treatment. Targeted nanoparticles can deliver drugs directly to cancer …
especially cancer treatment. Targeted nanoparticles can deliver drugs directly to cancer …
[HTML][HTML] HPV E6/E7 promotes aerobic glycolysis in cervical cancer by regulating IGF2BP2 to stabilize m6A-MYC expression
C Hu, T Liu, C Han, Y Xuan, D Jiang… - … journal of biological …, 2022 - ncbi.nlm.nih.gov
Enhanced aerobic glycolysis constitutes an additional source of energy for tumor
proliferation and metastasis. Human papillomavirus (HPV) infection is the main cause of …
proliferation and metastasis. Human papillomavirus (HPV) infection is the main cause of …
Single‐cell dissection of cervical cancer reveals key subsets of the tumor immune microenvironment
G Cao, J Yue, Y Ruan, Y Han, Y Zhi, J Lu, M Liu… - The EMBO …, 2023 - embopress.org
The tumor microenvironment (TME) directly determines patients' outcomes and therapeutic
efficiencies. An in‐depth understanding of the TME is required to improve the prognosis of …
efficiencies. An in‐depth understanding of the TME is required to improve the prognosis of …
SERPINH1 is a potential prognostic biomarker and correlated with immune infiltration: a pan-cancer analysis
Y Wang, W Gu, W Wen, X Zhang - Frontiers in genetics, 2022 - frontiersin.org
Background: Serpin peptidase inhibitor clade H, member 1 (SERPINH1) is a gene encoding
a member of the serpin superfamily of serine proteinase inhibitors. The upregulated of …
a member of the serpin superfamily of serine proteinase inhibitors. The upregulated of …
Single‐cell RNA‐sequencing dissects cellular heterogeneity and identifies two tumor‐suppressing immune cell subclusters in HPV‐related cervical adenosquamous …
X Li, M Zhang, T Lei, W Zou, R Huang… - Journal of Medical …, 2022 - Wiley Online Library
The intratumor heterogeneity of human papillomavirus (HPV)‐related cervical cancer
remains poorly defined. We performed single‐cell RNA sequencing on 18 046 individual …
remains poorly defined. We performed single‐cell RNA sequencing on 18 046 individual …
HPV-positive and-negative cervical cancers are immunologically distinct
Although infection with human papillomavirus (HPV) is associated with nearly all cervical
cancers (CC), a small proportion are HPV-negative. Recently, it has become clear that HPV …
cancers (CC), a small proportion are HPV-negative. Recently, it has become clear that HPV …
[PDF][PDF] m6A modification confers thermal vulnerability to HPV E7 oncotranscripts via reverse regulation of its reader protein IGF2BP1 upon heat stress
L Wang, G Zhan, Y Maimaitiyiming, Y Su, S Lin, J Liu… - Cell Reports, 2022 - cell.com
Human papillomavirus (HPV)-induced carcinogenesis critically depends on the viral early
protein 7 (E7), making E7 an attractive therapeutic target. Here, we report that the E7 …
protein 7 (E7), making E7 an attractive therapeutic target. Here, we report that the E7 …
Understanding cervical cancer at single-cell resolution
Cervical cancer is now the fourth most prevalent malignancy in women worldwide,
representing a tremendous burden of cancer. The heterogeneity of complex tumor …
representing a tremendous burden of cancer. The heterogeneity of complex tumor …
Enhancing the effect of nucleic acid vaccines in the treatment of HPV-related cancers: an overview of delivery systems
IA de Moura, AJD Silva, LS de Macêdo, MCV Invenção… - Pathogens, 2022 - mdpi.com
Prophylactic vaccines against human papillomavirus (HPV) have proven efficacy in those
who have not been infected by the virus. However, they do not benefit patients with …
who have not been infected by the virus. However, they do not benefit patients with …