DNA nanotechnology has progressed from proof-of-concept demonstrations of structural
design towards application-oriented research. As a natural material with excellent self …

Over the past decade, we have seen rapid advances in applying nanotechnology in
biomedical areas including bioimaging, biodetection, and drug delivery. As an emerging …

Aptamers are short single-stranded DNA or RNA oligonucleotides isolated from randomized
libraries, presenting high affinity and specificity toward targets with similar to antibodies …

Exploring and understanding biological and pathological changes are of great significance
for early diagnosis and therapy of diseases. Optical sensing and imaging approaches have …

Deoxyribonucleic acid (DNA) is a promising synthesizer for precisely constructing almost
arbitrary geometry in two and three dimensions. Among various DNA-based soft materials …

DNA hydrogels, which take advantage of the unique properties of functional DNA motifs,
such as specific molecular recognition, programmable and high‐precision assembly …

Precise nanomedicine has been extensively explored for efficient cancer imaging and
targeted cancer therapy, as evidenced by a few breakthroughs in their preclinical and …

Precision medicine holds great promise to harness genetic and epigenetic cues for targeted
treatment of a variety of diseases, ranging from many types of cancers, neurodegenerative …

The CRISPR-Cas9 genome-editing system is a part of the adaptive immune system in
archaea and bacteria to defend against invasive nucleic acids from phages and plasmids …

Isothermal amplification of nucleic acids is a simple process that rapidly and efficiently
accumulates nucleic acid sequences at constant temperature. Since the early 1990s …