[HTML][HTML] Deimmunization of protein therapeutics–Recent advances in experimental and computational epitope prediction and deletion
Biotherapeutics, and antimicrobial proteins in particular, are of increasing interest for human
medicine. An important challenge in the development of such therapeutics is their potential …
medicine. An important challenge in the development of such therapeutics is their potential …
[HTML][HTML] Advances of reverse vaccinology for mRNA vaccine design against SARS-CoV-2: a review of methods and tools
mRNA vaccines are a new class of vaccine that can induce potent and specific immune
responses against various pathogens. However, the design of mRNA vaccines requires the …
responses against various pathogens. However, the design of mRNA vaccines requires the …
[HTML][HTML] TANTIGEN 2.0: a knowledge base of tumor T cell antigens and epitopes
We previously developed TANTIGEN, a comprehensive online database cataloging more
than 1000 T cell epitopes and HLA ligands from 292 tumor antigens. In TANTIGEN 2.0, we …
than 1000 T cell epitopes and HLA ligands from 292 tumor antigens. In TANTIGEN 2.0, we …
[HTML][HTML] Epitope-Based Vaccine Target Screening against Highly Pathogenic MERS-CoV: An In Silico Approach Applied to Emerging Infectious Diseases
J Shi, J Zhang, S Li, J Sun, Y Teng, M Wu, J Li, Y Li… - PloS one, 2015 - journals.plos.org
Middle East respiratory syndrome coronavirus (MERS-CoV) with pandemic potential is a
major worldwide threat to public health. However, vaccine development for this pathogen …
major worldwide threat to public health. However, vaccine development for this pathogen …
[HTML][HTML] The role of major histocompatibility complex in organ transplantation-donor specific anti-major histocompatibility complex antibodies analysis goes to the next …
T Nakamura, T Shirouzu, K Nakata… - International journal of …, 2019 - mdpi.com
Organ transplantation has progressed with the comprehension of the major
histocompatibility complex (MHC). It is true that the outcome of organ transplantation largely …
histocompatibility complex (MHC). It is true that the outcome of organ transplantation largely …
[HTML][HTML] Relative rate and location of intra-host HIV evolution to evade cellular immunity are predictable
Human immunodeficiency virus (HIV) evolves within infected persons to escape being
destroyed by the host immune system, thereby preventing effective immune control of …
destroyed by the host immune system, thereby preventing effective immune control of …
A catalog of HLA type, HLA expression, and neo-epitope candidates in human cancer cell lines
Cancer cell lines are a tremendous resource for cancer biology and therapy development.
These multipurpose tools are commonly used to examine the genetic origin of cancers, to …
These multipurpose tools are commonly used to examine the genetic origin of cancers, to …
[HTML][HTML] Vaccinomic approach for novel multi epitopes vaccine against severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2)
YA Almofti, KA Abd-Elrahman, EEM Eltilib - BMC immunology, 2021 - Springer
Background The spread of a novel coronavirus termed severe acute respiratory syndrome
coronavirus-2 (SARS-CoV-2) in China and other countries is of great concern worldwide …
coronavirus-2 (SARS-CoV-2) in China and other countries is of great concern worldwide …
[HTML][HTML] Association between germ-line HLA and immune-related adverse events
N Jiang, Y Yu, M Zhang, Y Tang, D Wu… - Frontiers in …, 2022 - frontiersin.org
Background In recent years, significant progress has been made in immune checkpoint
inhibitors (ICIs). However, accompanied by remarkable efficacy, a growing number of …
inhibitors (ICIs). However, accompanied by remarkable efficacy, a growing number of …