Polymeric delivery of therapeutic nucleic acids
R Kumar, CF Santa Chalarca, MR Bockman… - Chemical …, 2021 - ACS Publications
The advent of genome editing has transformed the therapeutic landscape for several
debilitating diseases, and the clinical outlook for gene therapeutics has never been more …
debilitating diseases, and the clinical outlook for gene therapeutics has never been more …
Complex coacervate‐based materials for biomedicine
WC Blocher, SL Perry - Wiley Interdisciplinary Reviews …, 2017 - Wiley Online Library
There has been increasing interest in complex coacervates for deriving and transporting
biomaterials. Complex coacervates are a dense, polyelectrolyte‐rich liquid that results from …
biomaterials. Complex coacervates are a dense, polyelectrolyte‐rich liquid that results from …
Protein encapsulation using complex coacervates: what nature has to teach us
WC Blocher McTigue, SL Perry - Small, 2020 - Wiley Online Library
Protein encapsulation is a growing area of interest, particularly in the fields of food science
and medicine. The sequestration of protein cargoes is achieved using a variety of methods …
and medicine. The sequestration of protein cargoes is achieved using a variety of methods …
Transfer matrix model of pH effects in polymeric complex coacervation
AR Knoerdel, WC Blocher McTigue… - The Journal of Physical …, 2021 - ACS Publications
Oppositely charged polyelectrolytes can undergo an associative phase separation, in a
process known as polymeric complex coacervation. This phenomenon is driven by the …
process known as polymeric complex coacervation. This phenomenon is driven by the …
Nanostructured Lipid‐Based Films for Substrate‐Mediated Applications in Biotechnology
Amphiphilic in nature, lipids spontaneously self‐assemble into a range of nanostructures in
the presence of water. Among lipid self‐assembled structures, liposomes and supported …
the presence of water. Among lipid self‐assembled structures, liposomes and supported …
The benefit of poor mixing: kinetics of coacervation
Complex coacervation has become a prominent area of research in the fields of food
science, personal care, drug stabilization, and more. However, little has been reported on …
science, personal care, drug stabilization, and more. However, little has been reported on …
Bioinspired Antimicrobial Coatings from Peptide-Functionalized Liquid Crystalline Nanostructures
M Zabara, Q Ren, H Amenitsch… - ACS Applied Bio …, 2021 - ACS Publications
Surface-associated microbial infections and contaminations are a major challenge in
various fields including the food and health sectors. This study demonstrates the design of …
various fields including the food and health sectors. This study demonstrates the design of …
Soft Nanostructured Films for Actuated Surface‐Based siRNA Delivery
Substrate‐mediated gene delivery is an emerging technology that enables spatial control of
gene expression and localized delivery. This is of particular interest for siRNA where surface …
gene expression and localized delivery. This is of particular interest for siRNA where surface …
Co‐assembly behavior of oppositely charged thermoresponsive elastin‐like polypeptide block copolymers
The formation of complex coacervate core micelles (C3Ms) was observed by mixing two
oppositely charged elastin‐like polypeptides (ELP)‐based diblock copolymers, each …
oppositely charged elastin‐like polypeptides (ELP)‐based diblock copolymers, each …
Mussel adhesion‐inspired reverse transfection platform enhances osteogenic differentiation and bone formation of human adipose‐derived stem cells
Using small interfering RNA (siRNA) to regulate gene expression is an emerging strategy for
stem cell manipulation to improve stem cell therapy. However, conventional methods of …
stem cell manipulation to improve stem cell therapy. However, conventional methods of …