Genetically predicted 486 blood metabolites in relation to risk of colorectal cancer: a Mendelian randomization study
Z Yun, Z Guo, X Li, Y Shen, M Nan, Q Dong… - Cancer …, 2023 - Wiley Online Library
Background Metabolic disorders are a hallmark feature of cancer. However, the evidence for
the causality of circulating metabolites to promote or prevent colorectal cancer (CRC) is still …
the causality of circulating metabolites to promote or prevent colorectal cancer (CRC) is still …
A Review Concerning the Use of Etravirine and Darunavir in Translational Medicine
M Pereira, N Vale - International Journal of Translational Medicine, 2023 - mdpi.com
This comprehensive review explores two antiretroviral drugs, Etravirine (ETV) and Darunavir
(DRV), a non-nucleoside reverse transcriptase inhibitor and a protease inhibitor, that are …
(DRV), a non-nucleoside reverse transcriptase inhibitor and a protease inhibitor, that are …
Recruitment of hexahydroquinoline as anticancer scaffold targeting inhibition of wild and mutants EGFR (EGFRWT, EGFRT790M, and EGFRL858R)
Hexahydroquinoline (HHQ) scaffold was constructed and recruited for development of new
series of anticancer agents. Thirty-two new compounds were synthesised where x-ray …
series of anticancer agents. Thirty-two new compounds were synthesised where x-ray …
Identification of approved drugs with ALDH1A1 inhibitory potential aimed at enhancing chemotherapy sensitivity in cancer cells: an in-silico drug repurposing …
SK Paul, A Guendouzi, A Banerjee… - Journal of …, 2023 - Taylor & Francis
The aldehyde dehydrogenase 1A1 (ALDH1A1) also known as retinal dehydrogenase, is an
enzyme normally involved in the cellular metabolism, development and detoxification …
enzyme normally involved in the cellular metabolism, development and detoxification …
Atractylenolide II Suppresses Glycolysis and Induces Apoptosis by Blocking the PADI3-ERK Signaling Pathway in Endometrial Cancer Cells
S Tian, L Ren, C Liu, Z Wang - Molecules, 2024 - mdpi.com
Atractylenolide II (AT-II), the major bioactive compound of Atractylodes macrocephala,
exhibits anti-cancer activity against many types of tumors, but the roles and the potential …
exhibits anti-cancer activity against many types of tumors, but the roles and the potential …
Exploring Darunavir, Rilpivirine and Etravirine as Potential Therapies for Bladder Cancer: Efficacy and Synergistic Effects
M Pereira, N Vale - Biomedicines, 2024 - mdpi.com
This research explores the therapeutic efficacy of Darunavir (DRV), Rilpivirine (RPV), and
Etravirine (ETV) against UM-UC-5 bladder cancer cells, addressing the critical need for …
Etravirine (ETV) against UM-UC-5 bladder cancer cells, addressing the critical need for …