Evaluation of phytochemical, antibacterial, thrombolytic, anti-inflammatory, and cytotoxicity profile of Achyranthes aspera aerial part extracts

HA Ha, LA Al-Humaid, M Aldawsari, D Bharathi… - Environmental …, 2024 - Elsevier
This investigation was designed and performed to compare the phytochemical profiling,
activities of antibacterial, thrombolytic, anti-inflammatory, and cytotoxicity of methanol extract …

[HTML][HTML] The Phytochemical Screening and Biological Properties of Brassica napus L. var. napobrassica (Rutabaga) Seeds

J Ayadi, M Debouba, R Rahmani, J Bouajila - Molecules, 2023 - mdpi.com
Rutabaga, also known as swede and scientifically classified as Brassica napus
napobrassica, is a biennial edible root vegetable that belongs to the Brassica genus and is …

Polyphenol Fingerprint, Biological Activities, and In Silico Studies of the Medicinal Plant Cistus parviflorus L. Extract

FAA El-Shibani, GM Sulaiman, AS Abouzied… - ACS …, 2023 - ACS Publications
Cistus parviflorus L.(Cistaceae) is a medicinal plant with several folkloric applications,
including being used for urinary tract infections and as a food additive. In this study, the …

[HTML][HTML] Molecular pathways of rosmarinic acid anticancer activity in triple-negative breast cancer cells: a literature review

EK Konstantinou, AA Panagiotopoulos, K Argyri… - Nutrients, 2023 - mdpi.com
Breast cancer is the most frequent type of cancer in women. Oncogenic transcription factors
promote the overproduction of cellular adhesion molecules and inflammatory cytokines …

Experimental and Theoretical Insights on Chemopreventive Effect of the Liposomal Thymoquinone Against Benzo[a]pyrene-Induced Lung Cancer in Swiss Albino …

A Khan, MA Alsahli, MA Aljasir… - Journal of …, 2023 - Taylor & Francis
Purpose Thymoquinone (TQ), a phytoconstituent of Nigella sativa seeds, has been studied
extensively in various cancer models. However, TQ's limited water solubility restricts its …

Sirt1-dependent mitochondrial biogenesis supports therapeutic effects of 4-butyl-polyhydroxybenzophenone compounds against Nafld

J Song, L Ren, Z Ren, X Ren, Y Qi, Y Qin… - European Journal of …, 2023 - Elsevier
The mitochondria have been identified as key targets in nonalcoholic fatty liver disease
(NAFLD), one of the most prevalent chronic liver damage diseases globally. Meanwhile, the …

[HTML][HTML] Blockade of the SRC/STAT3/BCL-2 signaling axis sustains the cytotoxicity in human colorectal cancer cell lines induced by Dehydroxyhispolon methyl ether

YC Hsieh, YC Dai, KT Cheng, WT Yang, MV Ramani… - Biomedicines, 2023 - mdpi.com
Colorectal cancer (CRC) is the third most prevalent human cancer globally. 5-Fluorouracil (5-
FU)-based systemic chemotherapy is the primary strategy for advanced CRC treatment, yet …

Allosteric Activation of Transglutaminase 2 via Inducing an “Open” Conformation for Osteoblast Differentiation

Z Yang, XW Zhang, FF Zhuo, TT Liu, QW Luo… - Advanced …, 2023 - Wiley Online Library
Osteoblasts play an important role in the regulation of bone homeostasis throughout life.
Thus, the damage of osteoblasts can lead to serious skeletal diseases, highlighting the …

[HTML][HTML] Recent advancements in the discovery of small-molecule non-nucleoside inhibitors targeting SARS-CoV-2 RdRp

B Zhou, D Chen, T Zhang, C Song, X Zhang… - Biomedicine & …, 2024 - Elsevier
The RNA-dependent RNA polymerase (RdRp) of SARS-CoV-2 plays a pivotal role in the life
cycle of the novel coronavirus and stands as a significant and promising target for anti-SARS …

Research status of indole-modified natural products

SF Duan, L Song, HY Guo, H Deng, X Huang… - RSC Medicinal …, 2023 - pubs.rsc.org
Indole is a heterocyclic compound formed by the fusion of a benzene ring and pyrrole ring,
which has rich biological activity. Many indole-containing compounds have been sold on the …