Exploring Synergistic Inhibition of Inflammatory and Antioxidant Potential: Integrated In Silico and In Vitro Analyses of Garcinia mangostana, Curcuma comosa, and …

K Eawsakul, K Bunluepuech - Advances in Pharmacological …, 2024 - Wiley Online Library
Compared with the use of a single herb alone, herb combinations can significantly increase
their effectiveness in treating various diseases. The objective of this research was to …

Osthole accelerates osteoporotic fracture healing by inducing the osteogenesis–angiogenesis coupling of BMSCs via the Wnt/β‐catenin pathway

S Zheng, G Hu, J Zheng, Y Li, J Li - Phytotherapy Research, 2024 - Wiley Online Library
Osthole, a natural coumarin derivative, has been shown to have multiple pharmacological
activities. However, its effect on osteoporotic fracture has not yet been examined. This …

Decoding active compounds and molecular targets of herbal medicine by high-throughput metabolomics technology: A systematic review

Z Wang, S Guo, Y Cai, Q Yang, Y Wang, X Yu… - Bioorganic …, 2024 - Elsevier
Clinical experiences of herbal medicine (HM) have been used to treat a variety of human
intractable diseases. As the treatment of diseases using HM is characterized by multi …

Skeletal Transformations of Terpenoid Forskolin Employing an Oxidative Rearrangement Strategy

S Cheng, C Dong, Y Ma, X Xu… - The Journal of Organic …, 2024 - ACS Publications
The skeletal transformations of diterpenoid forskolin were achieved by employing an
oxidative rearrangement strategy. A library of 36 forskolin analogues with structural diversity …

Bakuchiol: A potential anticancer compound from Psoralea corylifolia linn

B Chopra, AK Dhingra, AS Grewal… - Anti-Cancer Agents …, 2023 - ingentaconnect.com
Background: Bakuchiol is a monoterpene phenol isolated from the seeds of Psoralea
corylifolia Linn. It is used traditionally in Indian and Chinese medicine and has been …

Design, synthesis and antimicrobial activity of novel berberine derivatives

BQ Zhang, FP Li, JX An, L Ma, YR Jin… - Pest Management …, 2024 - Wiley Online Library
BACKGROUND The threats to the safety of humans and the environment and the resistance
of agricultural chemicals to plant pathogenic fungi and bacteria highlight an urgent need to …

[HTML][HTML] Antcin-H, a natural triterpene derived from Antrodia cinnamomea, ameliorates dextran sulfate sodium-induced colitis in mice by inhibiting the NLRP3 …

WT Wong, LH Li, HW Chiu, MP Menon, HT Hsu… - Journal of Traditional …, 2024 - Elsevier
Inflammatory bowel disease (IBD) comprises idiopathic intestinal disorders, including
ulcerative colitis and Crohn's disease. Patients with IBD experience a significantly reduced …

Unearthing the therapeutic benefits of culinary‐medicinal mushrooms for humans: Emerging sustainable bioresources of 21st century

L Thomas, P Mago - Journal of Basic Microbiology, 2024 - Wiley Online Library
Global interest in mushroom farming techniques has grown in the last few years. Despite not
making up a large amount of the human diet at the moment, the nutritional worth of …

Activity-based protein profiling in drug/pesticide discovery: Recent advances in target identification of antibacterial compounds

K Chen, L Zhang, Y Ding, Z Sun, J Meng, R Luo… - Bioorganic …, 2024 - Elsevier
Given the escalating incidence of bacterial diseases and the challenge posed by pathogenic
bacterial resistance, it is imperative to identify appropriate methodologies for conducting …

[HTML][HTML] Conjoint research of WGCNA, single-cell transcriptome and structural biology reveals the potential targets of IDD development and treatment and JAK3 …

Y Zhao, Y Mu, Y Zou, Z He, T Lu, X Wang, W Li… - Aging (Albany …, 2023 - ncbi.nlm.nih.gov
Objectives: This study conducted integrated analysis of bulk RNA sequencing, single-cell
RNA sequencing and Weighted Gene Co-expression Network Analysis (WGCNA), to …