Contingency and determinism in evolution: Replaying life's tape
BACKGROUND Evolution is a strongly historical process, and evolutionary biology is a field
that combines history and science. How the historical nature of evolution affects the …
that combines history and science. How the historical nature of evolution affects the …
Experimental evolution and the dynamics of adaptation and genome evolution in microbial populations
RE Lenski - The ISME journal, 2017 - academic.oup.com
Evolution is an on-going process, and it can be studied experimentally in organisms with
rapid generations. My team has maintained 12 populations of Escherichia coli in a simple …
rapid generations. My team has maintained 12 populations of Escherichia coli in a simple …
The dynamics of molecular evolution over 60,000 generations
The outcomes of evolution are determined by a stochastic dynamical process that governs
how mutations arise and spread through a population. However, it is difficult to observe …
how mutations arise and spread through a population. However, it is difficult to observe …
[HTML][HTML] Sugar synthesis from CO2 in Escherichia coli
Can a heterotrophic organism be evolved to synthesize biomass from CO 2 directly? So far,
non-native carbon fixation in which biomass precursors are synthesized solely from CO 2 …
non-native carbon fixation in which biomass precursors are synthesized solely from CO 2 …
Revisiting the Design of the Long-Term Evolution Experiment with Escherichia coli
RE Lenski - Journal of Molecular Evolution, 2023 - Springer
The long-term evolution experiment (LTEE) with Escherichia coli began in 1988 and it
continues to this day, with its 12 populations having recently reached 75,000 generations of …
continues to this day, with its 12 populations having recently reached 75,000 generations of …
A conformational switch in the SCF-D3/MAX2 ubiquitin ligase facilitates strigolactone signalling
Strigolactones (SLs) are a class of plant hormones that regulate numerous processes of
growth and development. SL perception and signal activation involves interaction between F …
growth and development. SL perception and signal activation involves interaction between F …
[HTML][HTML] Contingency and chance erase necessity in the experimental evolution of ancestral proteins
The roles of chance, contingency, and necessity in evolution are unresolved because they
have never been assessed in a single system or on timescales relevant to historical …
have never been assessed in a single system or on timescales relevant to historical …
Recent insights into the world of dual‐function bacterial sRNAs
SB Schnoor, P Neubauer… - Wiley Interdisciplinary …, 2024 - Wiley Online Library
Dual‐function sRNAs refer to a small subgroup of small regulatory RNAs that merges base‐
pairing properties of antisense RNAs with peptide‐encoding properties of mRNA. Both …
pairing properties of antisense RNAs with peptide‐encoding properties of mRNA. Both …
[HTML][HTML] Historical contingency in the evolution of antibiotic resistance after decades of relaxed selection
Populations often encounter changed environments that remove selection for the
maintenance of particular phenotypic traits. The resulting genetic decay of those traits under …
maintenance of particular phenotypic traits. The resulting genetic decay of those traits under …
On the deformability of an empirical fitness landscape by microbial evolution
A fitness landscape is a map between the genotype and its reproductive success in a given
environment. The topography of fitness landscapes largely governs adaptive dynamics …
environment. The topography of fitness landscapes largely governs adaptive dynamics …