Microbiome risk profiles as biomarkers for inflammatory and metabolic disorders

A Metwaly, S Reitmeier, D Haller - Nature reviews Gastroenterology & …, 2022 - nature.com
The intestine harbours a complex array of microorganisms collectively known as the gut
microbiota. The past two decades have witnessed increasing interest in studying the gut …

[HTML][HTML] Role of microbiota-derived short-chain fatty acids in cancer development and prevention

R Mirzaei, A Afaghi, S Babakhani, MR Sohrabi… - Biomedicine & …, 2021 - Elsevier
Following cancer, cells in a particular tissue can no longer respond to the factors involved in
controlling cell survival, differentiation, proliferation, and death. In recent years, it has been …

Human gut microbiota and gastrointestinal cancer

C Meng, C Bai, TD Brown, LE Hood… - Genomics, Proteomics …, 2018 - academic.oup.com
Human gut microbiota play an essential role in both healthy and diseased states of humans.
In the past decade, the interactions between microorganisms and tumors have attracted …

The microbiome and breast cancer: a review

J Chen, J Douglass, V Prasath, M Neace… - Breast cancer research …, 2019 - Springer
The human microbiome plays an integral role in physiology, with most microbes considered
benign or beneficial. However, some microbes are known to be detrimental to human health …

Modulation of gut microbiota combined with upregulation of intestinal tight junction explains anti-inflammatory effect of corylin on colitis-associated cancer in mice

ZY Chang, HM Liu, YL Leu, CH Hsu… - International journal of …, 2022 - mdpi.com
Inflammatory bowel disease (IBD) involves chronic inflammation, loss of epithelial integrity,
and gastrointestinal microbiota dysbiosis, resulting in the development of a colon cancer …

[HTML][HTML] Linking gut microbiota to colorectal cancer

H Raskov, J Burcharth, HC Pommergaard - Journal of cancer, 2017 - ncbi.nlm.nih.gov
Pre-clinical and clinical data produce mounting evidence that the microbiota is strongly
associated with colorectal carcinogenesis. Dysbiosis may change the course of …

Colorectal cancer is associated with increased circulating lipopolysaccharide, inflammation and hypercoagulability

GM De Waal, WJS De Villiers, T Forgan, T Roberts… - Scientific reports, 2020 - nature.com
Gut dysbiosis contributes to the development of a dysfunctional gut barrier, facilitating the
translocation of bacteria and inflammagens, and is implicated in colorectal cancer (CRC) …

Increased risk of diabetes in inflammatory bowel disease patients: a nationwide population-based study in Korea

EA Kang, K Han, J Chun, H Soh, S Park, JP Im… - Journal of clinical …, 2019 - mdpi.com
The association of diabetes with inflammatory bowel disease (IBD) remains unclear. The risk
of diabetes in patients with IBD compared with non-IBD controls was investigated. Using the …

The gut microbiota metabolite urolithin A inhibits NF-κB activation in LPS stimulated BMDMs

KNM Abdelazeem, MZ Kalo, S Beer-Hammer… - Scientific Reports, 2021 - nature.com
Inflammation is a natural defense process of the innate immune system, associated with the
release of proinflammatory cytokines such as interleukin-1β, interleukin-6, interleukin-12 …

Dipeptidyl peptidase-4 inhibitors and incidence of inflammatory bowel disease among patients with type 2 diabetes: population based cohort study

D Abrahami, A Douros, H Yin, OHY Yu, C Renoux… - bmj, 2018 - bmj.com
Objective To assess whether the use of dipeptidyl peptidase-4 inhibitors is associated with
the incidence of inflammatory bowel disease in patients with type 2 diabetes. Design …