Chemoenzymatic methods for the synthesis of glycoproteins

C Li, LX Wang - Chemical reviews, 2018 - ACS Publications
Glycosylation is one of the most prevalent posttranslational modifications that profoundly
affects the structure and functions of proteins in a wide variety of biological recognition …

Toward automated enzymatic synthesis of oligosaccharides

L Wen, G Edmunds, C Gibbons, J Zhang… - Chemical …, 2018 - ACS Publications
Oligosaccharides together with oligonucleotides and oligopeptides comprise the three major
classes of natural biopolymers. Automated systems for oligonucleotide and oligopeptide …

“Sweet flavonoids”: Glycosidase-catalyzed modifications

K Slámová, J Kapešová, K Valentová - International Journal of Molecular …, 2018 - mdpi.com
Natural flavonoids, especially in their glycosylated forms, are the most abundant phenolic
compounds found in plants, fruit, and vegetables. They exhibit a large variety of beneficial …

Enzymatic polymer synthesis: an opportunity for green polymer chemistry

S Kobayashi, A Makino - Chemical reviews, 2009 - ACS Publications
Polymeric materials, natural and unnatural, are indispensable to the modern society. They
are widely used from everyday life usages as commodity materials to industry and …

Substituent effects on in vitro antioxidizing properties, stability, and solubility in flavonoids

M Plaza, T Pozzo, J Liu, KZ Gulshan Ara… - Journal of agricultural …, 2014 - ACS Publications
Antioxidants are widely used by humans, both as dietary supplements and as additives to
different types of products. The desired properties of an antioxidant often include a balance …

Advances in enzymatic glycoside synthesis

PM Danby, SG Withers - ACS chemical biology, 2016 - ACS Publications
A robust platform for facile defined glycan synthesis does not exist. Yet the need for such
technology has never been greater as researchers seek to understand the full scope of …

Enzymatic methods for glyco (diversification/randomization) of drugs and small molecules

RW Gantt, P Peltier-Pain, JS Thorson - Natural product reports, 2011 - pubs.rsc.org
Covering: up to the end of May 2011 Glyco (randomization/diversification) is a term that
encompasses strategies to diversify a core drug scaffold via enzymatic glycosylation to …

Enzymes in the synthesis of glycoconjugates

RM Schmaltz, SR Hanson, CH Wong - Chemical reviews, 2011 - ACS Publications
Aims This review is intended to update our previous discussion on the chemoenzymatic
synthesis of carbohydrates and glycoconjugates,(1) with new emphasis placed on …

Enzymatic glycosylation of small molecules: challenging substrates require tailored catalysts

T Desmet, W Soetaert, P Bojarová… - … A European Journal, 2012 - Wiley Online Library
Glycosylation can significantly improve the physicochemical and biological properties of
small molecules like vitamins, antibiotics, flavors, and fragrances. The chemical synthesis of …

Precision polysaccharide synthesis catalyzed by enzymes

J Kadokawa - Chemical reviews, 2011 - ACS Publications
Precision Polysaccharide Synthesis Catalyzed by Enzymes | Chemical Reviews ACS ACS
Publications C&EN CAS Find my institution Log In Chemical Reviews ACS Publications. Most …