Review of current transfusion therapy and blood banking practices

EK Storch, BS Custer, MR Jacobs, JE Menitove… - Blood reviews, 2019 - Elsevier
Transfusion Medicine is a dynamically evolving field. Recent high-quality research has
reshaped the paradigms guiding blood transfusion. As increasing evidence supports the …

How I use platelet transfusions

SJ Stanworth, A Shah - Blood, The Journal of the American …, 2022 - ashpublications.org
Platelet transfusions are commonly administered for the prevention or treatment of bleeding
in patients with acquired thrombocytopenia across a range of clinical contexts. Recent data …

Thrombocytopenia in intensive care unit patients: a scoping review

AB Jonsson, SL Rygård, T Hildebrandt… - Acta …, 2021 - Wiley Online Library
Background Thrombocytopenia is frequent in intensive care unit (ICU) patients and may be
associated with adverse outcomes. We aimed to assess the incidence, risk factors, and …

Thromboelastography predicts thromboembolism in critically ill coagulopathic patients

Y Harahsheh, OC Duff, KM Ho - Critical Care Medicine, 2019 - journals.lww.com
Objectives: Critically ill patients with deranged conventional coagulation tests are often
perceived to have an increased bleeding risk. Whether anticoagulant prophylaxis for these …

Prophylactic versus restrictive platelet transfusion strategy in patients with haematological malignancies in the ICU setting, a propensity-score analysis

JB Berenger, C Saillard, A Sannini, L Servan… - Journal of Critical …, 2024 - Elsevier
Purpose Prophylactic platelet transfusions (PT) aim to reduce bleeding. We assessed
whether restrictive PT compared to prophylactic strategy could apply in ICU. Material and …

The association between platelet transfusions and mortality in patients with critical illness

S Ning, Y Liu, R Barty, R Cook, B Rochwerg… - …, 2019 - Wiley Online Library
BACKGROUND Platelet (PLT) transfusions are frequently administered in the setting of
critical illness but their clinical impacts remain unknown. This study examined the …

[HTML][HTML] Anticoagulation in thrombocytopenic patients–Time to rethink?

J Thachil, M Carrier, T Lisman - Journal of Thrombosis and Haemostasis, 2022 - Elsevier
One of the difficult clinical situations in the anticoagulation era is how to give these
medications to patients with significantly reduced platelet counts. The concern is the …

Lower platelet count and metastatic tumor are associated with increased risk of spontaneous bleeding in critically ill patients with cancer: An observational study

SS Kayano, PV Santana, R Colella, MP Colella… - …, 2023 - Wiley Online Library
Background Thrombocytopenia is common in critically ill patients with cancer. However, the
association of platelet count with spontaneous bleeding is controversial in critically ill …

Prophylactic platelet transfusions in critical care: How low can you go?

A Shah, SJ Stanworth, JC Doidge… - Journal of the …, 2024 - journals.sagepub.com
Platelet transfusions have risks and are the most com monly implicated component
associated with transfusion reactions. 1 Febrile nonhaemolytic transfusion reactions and …

A UK national survey of prophylactic platelet transfusion thresholds in non-bleeding, critically ill adults

A Shah, DW Gould, J Doidge, PR Mouncey… - medRxiv, 2020 - medrxiv.org
Thrombocytopaenia is common in critically ill patients and associated with poor clinical
outcomes. Current guideline recommendations for prophylactic platelet transfusions, to …