Simple Summary Integrins, a superfamily of cell adhesion receptors, were extensively
investigated as therapeutic targets over the last decades, motivated by their multiple …

Alginate is a biomaterial that has found numerous applications in biomedical science and
engineering due to its favorable properties, including biocompatibility and ease of gelation …

A bird's eye view is now demanded in the area of cancer research to suppress the suffering
of cancer patient and mediate the lack of treatment related to chemotherapy. Chemotherapy …

The integrin αvβ3 plays an important role in angiogenesis. It is expressed on tumoral
endothelial cells as well as on some tumor cells. RGD peptides are well-known to bind …

The advent of nanotechnology has opened new possibilities for bioimaging. Metal
nanoparticles (such as gold, silver, iron, copper, etc.) hold tremendous potential and offer …

Peptides of natural and synthetic sources are compounds operating in a wide range of
biological interactions. They play a key role in biotechnological applications as both …

Receptor-based radiopharmaceuticals are of great current interest in molecular imaging and
radiotherapy of cancers, and provide a unique tool for target-specific delivery of …

The majority of clinically approved anticancer drugs are characterized by a narrow
therapeutic window that results mainly from a high systemic toxicity of the drugs in …

Arginine-Glycine-Aspartic (RGD), is the specific recognition site of integrins with theirs
ligands, and regulates cell-cell and cell-extracellular matrix interactions. The RGD motif can …

Fluorescence targeted imaging in vivo has proven useful in tumor recognition and drug
delivery. In the process of in vivo imaging, however, a high autofluorescence background …