Human adipose tissue-derived stem/stromal cells (hASCs) are adult multipotent
mesenchymal stem/stromal cells with immunomodulatory capacities. Here, we present up-to …

Adipose tissue plays an important role in systemic energy metabolism, and its dysfunction
can lead to severe metabolic disorders. Various cells in adipose tissue communicate with …

A set of 5-(substituted benzylidene) thiazolidine-2, 4-dione derivatives was explored to study
the main structural requirement for the design of protein tyrosine phosphatase 1B (PTP1B) …

Diabetes mellitus is a highly prevalent disease characterized by hyperglycaemia that
damages the vascular system, leading to micro‐(retinopathy, neuropathy, nephropathy) and …

本研究在高脂饮食(high-fat diet, HFD) 饲喂和链脲佐菌素(streptozotin, STZ)
注射的联合作用下成功建立小鼠及犬糖尿病模型, 旨在探究米托蒽醌甲磺酸盐(mitoquionl …

Background Diabetes mellitus (DM) is a global epidemic with increasing incidences. DM is a
metabolic disease associated with chronic hyperglycemia. Aside from conventional …

Aims Generation of mature β-cells from MSCs has been a challenge in the field of stem cell
therapy of diabetes. Adipose tissue-derived mesenchymal stem cells (Ad-MSCs) have made …

Abstract Type 1 diabetes (T1D) is a chronic autoimmune condition that affects millions of
people worldwide. Insulin pumps or injections are the standard treatment options for this …

Introduction: Stem cells can be used to treat diabetic mellitus and complications. ω3-
docosahexaenoic acid (DHA) derived lipid mediators are inflammation-resolving and …

Diabetes mellitus (DM), a chronic metabolic disease, poses a significant global health
challenge, with current treatments often fail to prevent the long-term disease complications …