Cofactor‐driven cascade reactions enable the efficient preparation of sugar nucleotides
Y Zheng, J Zhang, J Meisner, W Li… - Angewandte Chemie …, 2022 - Wiley Online Library
Glycosylation is catalyzed by glycosyltransferases using sugar nucleotides or occasionally
lipid‐linked phosphosugars as donors. However, only very few common sugar nucleotides …
lipid‐linked phosphosugars as donors. However, only very few common sugar nucleotides …
A “One-Step” Strategy for the Global Characterization of Core-Fucosylated Glycoproteome
Y Wang, R Yuan, B Liang, J Zhang, Q Wen, H Chen… - JACS Au, 2024 - ACS Publications
Core fucosylation, a special type of N-linked glycosylation, is important in tumor proliferation,
invasion, metastatic potential, and therapy resistance. However, the core-fucosylated …
invasion, metastatic potential, and therapy resistance. However, the core-fucosylated …
A Sensitive and Reversible Labeling Strategy Enables Global Mapping of the Core‐Fucosylated Glycoproteome on Cell Surfaces
Y Tian, Y Wang, H Yin, Y Luo, F Wei… - Angewandte …, 2022 - Wiley Online Library
Core fucosylation, the attachment of α1, 6‐fucose to the innermost N‐acetylglucosamine
(GlcNAc) residue of N‐glycans, has a strong relationship with tumor growth, invasion …
(GlcNAc) residue of N‐glycans, has a strong relationship with tumor growth, invasion …
Sugar nucleotide regeneration system for the synthesis of Bi-and triantennary N-glycans and exploring their activities against siglecs
MT Anwar, SK Kawade, YR Huo, AK Adak… - European Journal of …, 2022 - Elsevier
Enzymatic synthesis that is commenced by the sugar nucleotide regeneration system
(SNRS) protocol can minimize 1) the consumption of exorbitant sugar nucleotides, 2) the …
(SNRS) protocol can minimize 1) the consumption of exorbitant sugar nucleotides, 2) the …
Systematic Enzymatic Synthesis of dTDP‐Activated Sugar Nucleotides
F Wei, R Yuan, Q Wen, L Wen - … Chemie International Edition, 2023 - Wiley Online Library
Deoxythymidine diphosphate (dTDP)‐activated sugar nucleotides are the most diverse
sugar nucleotides in nature. They serve as the glycosylation donors of glycosyltransferases …
sugar nucleotides in nature. They serve as the glycosylation donors of glycosyltransferases …
Glyco-Engineering Cell Surfaces by Exo-Enzymatic Installation of GlcNAz and LacNAz Motifs
FV De Leon Gonzalez, ME Boddington… - ACS Chemical …, 2024 - ACS Publications
Exo-enzymatic glyco-engineering of cell-surface glycoconjugates enables the selective
display of well-defined glyco-motifs bearing bioorthogonal functional groups, which can be …
display of well-defined glyco-motifs bearing bioorthogonal functional groups, which can be …
Biocatalytic approaches to building blocks for enzymatic and chemical glycan synthesis
While the field of biocatalysis has bloomed over the past 20–30 years, advances in the
understanding and improvement of carbohydrate-active enzymes, in particular, the sugar …
understanding and improvement of carbohydrate-active enzymes, in particular, the sugar …
Gram-scale production of sugar nucleotides and their derivatives
S Li, S Wang, Y Wang, J Qu, X Liu, PG Wang… - Green Chemistry, 2021 - pubs.rsc.org
Here, we report a practical sugar nucleotide production strategy that combined a high-
concentrated multi-enzyme catalyzed reaction and a robust chromatography-free selective …
concentrated multi-enzyme catalyzed reaction and a robust chromatography-free selective …
Resin-free peptide synthesis mediated by tri (4-benzoylphenyl) phosphate (TBP) derivatives as small-molecule supports
H Li, J Chao, G Tian, J Hasan, Y Jin… - Organic Chemistry …, 2020 - pubs.rsc.org
In this paper, a series of novel tri (4-benzoylphenyl) phosphate derivatives with unique
precipitation-inducing properties were synthesized and used as C-terminal supports for …
precipitation-inducing properties were synthesized and used as C-terminal supports for …
Chemoenzymatic synthesis of homogeneous chondroitin polymers and its derivatives
Y Wang, S Li, X Xu, Y Tan, X Liu, J Fang - Carbohydrate polymers, 2020 - Elsevier
Chondroitin sulfate is a linear glycosaminoglycan widely distributed as an important
extracellular matrix component of mammalian cells. It participates in numerous pathological …
extracellular matrix component of mammalian cells. It participates in numerous pathological …