[HTML][HTML] Recent advances in photoaffinity labeling strategies to capture Glycan–Protein interactions

JL Babulic, FVDL González, CJ Capicciotti - Current Opinion in Chemical …, 2024 - Elsevier
Glycans decorate all cells and are critical mediators of cellular processes through
recognition by glycan-binding proteins (GBPs). While targeting glycan–protein interactions …

Synthesis of selected unnatural sugar nucleotides for biotechnological applications

M Qiao, B Li, Y Ji, L Lin, R Linhardt… - Critical reviews in …, 2021 - Taylor & Francis
Sugar nucleotides are the principal building blocks for the synthesis of most complex
carbohydrates and are crucial intermediates in carbohydrate metabolism. Uridine …

Process Development for the Enzymatic Gram‐Scale Production of the Unnatural Nucleotide Sugar UDP‐6‐Azido‐GalNAc

H Frohnmeyer, JMM Verkade, M Spiertz… - …, 2024 - Wiley Online Library
Azido sugars hold great promise as substrates in numerous click‐chemistry applications.
However, the synthesis of activated azido sugars is limited by cost and complexity …

N–Si Heterolysis by Chiral (BOX)Cu(OTf)2 Catalysts for the Synthesis of Indole and Carbazole Glycosides

N Romano, TL McMinn, MR Gagné - Organic Letters, 2024 - ACS Publications
Chiral Cu (II) bisoxazolines have been shown to catalyze the coupling of acetyl-protected
carbohydrates with N-silylated indoles to give the corresponding N-glycosides. Preliminary …

Facile Enzymatic Synthesis of Diverse Naturally-Occurring β-d-Mannopyranosides Catalyzed by Glycoside Phosphorylases

J Liu, X Yin, Z Li, X Wu, Z Zheng, J Fang, G Gu… - ACS …, 2021 - ACS Publications
β-d-Mannopyranosides are essential components of protein N-glycans, plant β-mannans,
and various pathogen surface antigens. Despite their significant biological roles, the …

Chemical reporters to study mammalian O-glycosylation

KE Huxley, LI Willems - Biochemical Society Transactions, 2021 - portlandpress.com
Glycans play essential roles in a range of cellular processes and have been shown to
contribute to various pathologies. The diversity and dynamic nature of glycan structures and …

Kinetic and NMR spectroscopic study of the chemical stability and reaction pathways of sugar nucleotides

J Jaakkola, A Nieminen, H Kivelä… - … Nucleotides & Nucleic …, 2020 - Taylor & Francis
The alkaline cleavage of two types of sugar nucleotides has been studied by 1H and 31P
NMR in order to obtain information on the stability and decomposition pathways in aqueous …

[PDF][PDF] Developing chemical tools to study ribitol-5-phosphate within cell-surface glycans

K Huxley - 2022 - etheses.whiterose.ac.uk
Glycans play essential roles in a range of cellular processes and have been shown to
contribute to various pathologies. The diversity and dynamic nature of glycan structures and …

[图书][B] Steric-Free Bioorthogonal Labeling of Post-translational Modification Substrates Based on A Fluorine-Thiol/Selenol Displacement Reaction

Z Lyu - 2021 - search.proquest.com
Post-translational modifications (PTMs) diversify the functions and control the stability of
proteins by the covalent addition of chemical groups or proteins. These modifications …