Well over a hundred reports have been published describing use of synthetic small-
interfering RNAs (siRNAs) in animals. The majority of these reports employed unmodified …

Liposomes are the leading drug delivery systems for the systemic (iv.) administration of
drugs. There are now liposomal formulations of conventional drugs that have received …

The immature plasmacytoid dendritic cell (PDC) is identical with the principal type I IFN‐
producing cell upon viral infection. Oligodeoxynucleotides which contain unmethylated CpG …

The recent acceleration in the identification and characterisation of new molecular targets for
cancer and the limited effectiveness of conventional treatment strategies has focused …

US7534772B2 - Methods for enhancing antibody-induced cell lysis and treating cancer -
Google Patents US7534772B2 - Methods for enhancing antibody-induced cell lysis and …

Cationic liposomes are lipid-bilayer vesicles with a positive surface charge that have re-
emerged as a promising new adjuvant technology. Although there is some evidence that …

This review describes the status of a local plasmid-based gene transfer technology known
as the gene activated matrix (GAM). Studies over the past 6 years suggest that GAM may …

2001-12-26 Assigned to COLEY PHARMACEUTICAL GROUP, INC. reassignment COLEY
PHARMACEUTICAL GROUP, INC. ASSIGNMENT OF ASSIGNORS INTEREST (SEE …

Multiple factors, including expression of costimulatory molecules, antigen-presenting
molecules, and target antigens, likely impact the efficacy of antibody therapy and other …

Recent reports support the concept that the major defect in polymicrobial sepsis is an
impaired immunologic response to infection. Oligodeoxynucleotides containing CpG …