In recent years, microphysiological system (MPS, also known as, organ-on-a-chip or tissue
chip) platforms have emerged with great promise to improve the predictive capacity of …

This review summarizes approaches used in tissue engineering and regenerative medicine,
with a focus on dental applications. Dental caries and periodontal disease are the most …

Organoids, which exhibit spontaneous organ specific organization, function, and multi-
cellular complexity, are in essence the in vitro reproduction of specific in vivo organ systems …

When decellularizing kidneys, it is important to maintain the integrity of the acellular
extracellular matrix (ECM), including associated adhesion proteins and growth factors that …

The pluripotent property of human embryonic stem cells (hESCs) makes them attractive for
treatment of degenerative diseases such as diabetes. We have developed a stage-wise …

A shortage of donor organs for transplantation and the dependence of the recipients on
immunosuppressive therapy have motivated researchers to consider alternative …

Dental tissue-derived mesenchymal stem cells have been proposed as an alternative
source for mesenchymal stem cells. Here, we investigated the differentiation ability toward …

The liver is the primary organ responsible for the detoxification and metabolism of drugs. To
date, a lack of preclinical models that accurately emulate drug metabolism by the human …

Although endothelial cells have been shown to affect mouse pancreatic development, their
precise function in human development remains unclear. Using a coculture system …

Human pluripotent stem cells, including human embryonic stem cells (hESCs) and human
induced pluripotent stem cells (hiPSCs), hold promise as novel therapeutic tools for diabetes …