The mechanism of dendritic cell-T cell crosstalk in rheumatoid arthritis

Z Wang, J Zhang, F An, J Zhang, X Meng, S Liu… - Arthritis Research & …, 2023 - Springer
Rheumatoid arthritis (RA) is a chronic inflammatory disease characterised by joint pain and
swelling, synovial hyperplasia, cartilage damage, and bone destruction. The mechanisms of …

Insights into the pathogenic role of neutrophils in systemic lupus erythematosus

S Ma, W Jiang, X Zhang, W Liu - Current Opinion in …, 2023 - journals.lww.com
Insights into the pathogenic role of neutrophils in systemic... : Current Opinion in
Rheumatology Insights into the pathogenic role of neutrophils in systemic lupus …

Soluble TREM2 triggers microglial dysfunction in neuromyelitis optica spectrum disorders

C Qin, M Chen, MH Dong, S Yang, H Zhang, YF You… - Brain, 2024 - academic.oup.com
Microglia-mediated neuroinflammation contributes to acute demyelination in neuromyelitis
optica spectrum disorders (NMOSD). Soluble triggering receptor expressed on myeloid cells …

PKM2 promotes proinflammatory macrophage activation in ankylosing spondylitis

W Weng, Y Zhang, L Gui, J Chen, W Zhu… - Journal of Leukocyte …, 2023 - academic.oup.com
Macrophages play a critical role in ankylosing spondylitis by promoting autoimmune tissue
inflammation through various effector functions. The inflammatory potential of macrophages …

SIRT2-PFKP interaction dysregulates phagocytosis in macrophages with acute ethanol-exposure

A Gandhirajan, S Roychowdhury, C Kibler… - Frontiers in …, 2023 - frontiersin.org
Alcohol abuse, reported by 1/8th critically ill patients, is an independent risk factor for death
in sepsis. Sepsis kills over 270,000 patients/year in the US. We reported that the ethanol …

Exosomal miRNAs-mediated macrophage polarization and its potential clinical application

M yun Yu, H jie Jia, J Zhang, G he Ran, Y Liu… - International …, 2023 - Elsevier
Macrophages are highly heterogeneous and plastic immune cells that play an important role
in the fight against pathogenic microorganisms and tumor cells. After different stimuli …

Immune response of silver pomfret (Pampus argenteus) to Photobacterium damselae subsp. Damselae: Virulence factors might induce immune escape by damaging …

Y Zhang, J Hu, K Yan, F Yuan, Y Li, M Zhang, Y Li… - Aquaculture, 2024 - Elsevier
Photobacterium damselae subsp. damselae (PDD) is a dangerous bacterial disease that
affects silver pomfret (Pampus argenteus) and its main virulence factors are pore-forming …

[HTML][HTML] Exploring the Potential of Glycolytic Modulation in Myeloid-Derived Suppressor Cells for Immunotherapy and Disease Management

J Kim, JY Choi, H Min, KW Hwang - Immune network, 2024 - ncbi.nlm.nih.gov
Recent advancements in various technologies have shed light on the critical role of
metabolism in immune cells, paving the way for innovative disease treatment strategies …

Dry and wet experiments reveal diagnostic clustering and immune landscapes of cuproptosis patterns in patients with ankylosing spondylitis

P Zhang, H Chen, Y Zhang, Y Liu, G Zhu… - International …, 2024 - Elsevier
Cuproptosis is a new manner of mitochondrial cell death induced by copper. There is
evidence that serum copper has a crucial impact on ankylosing spondylitis (AS) by copper …

The causes and consequences of trained immunity in myeloid cells

G Bhargavi, S Subbian - Frontiers in immunology, 2024 - frontiersin.org
Conventionally, immunity in humans has been classified as innate and adaptive, with the
concept that only the latter type has an immunological memory/recall response against …